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Carcinoid tumours and carcinoid syndrome

Introduction: Carcinoid tumours and carcinoid syndrome

Description of Carcinoid tumours and carcinoid syndrome

Carcinoid tumours and carcinoid syndrome: Carcinoid tumor, also known as well differentiated endocrine neoplasm, is a slow growing neuroendocrine tumor, composed of uniform, round, or polygonal cells having monotonous, centrally located nuclei and small nucleoli, infrequent mitoses, and no necrosis. The tumor may show a variety of patterns, such as solid, trabecular, and acinar. Electron microscopy shows small secretory granules. Immunohistochemical studies reveal NSE, as well as chromogranin immunoreactivity. Malignant histology (cellular pleomorphism, hyperchromatic nuclei, prominent nucleoli, necrosis, and mitoses) can occasionally be seen. Such cases may have an aggressive clinical course. Gastrointestinal tract and lung are common sites of involvement.
Source: Diseases Database

Carcinoid tumours and carcinoid syndrome: Related Topics

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