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Dictionary » Chronic myeloid leukaemia

Chronic myeloid leukaemia

Introduction: Chronic myeloid leukaemia

Description of Chronic myeloid leukaemia

Chronic myeloid leukaemia: The most common chronic myeloproliferative disorder characterized by neutrophilic leukocytosis. It is associated with the Philadelphia (Ph) chromosome and/or the BCR/ABL fusion gene. Most patients are middle-aged or elderly. Common findings at presentation include fatigue, weight loss, anemia, night sweats, and splenomegaly. The disease is bi- or triphasic: an initial indolent chronic phase is followed by accelerated or blast phase. Allogeneic bone marrow transplantation is currently the only curative therapy (adapted from WHO 2001). -- 2003
Source: Diseases Database

Chronic myeloid leukaemia: Related Topics

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