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Dictionary » Complement Pathway, Classical

Complement Pathway, Classical

Introduction: Complement Pathway, Classical

Description of Complement Pathway, Classical

Complement Pathway, Classical: Complement activation initiated by the binding of COMPLEMENT C1 to ANTIGEN-ANTIBODY COMPLEXES at the COMPLEMENT C1Q subunit. This leads to the sequential activation of COMPLEMENT C1R and COMPLEMENT C1S subunits. Activated C1s cleaves COMPLEMENT C4 and COMPLEMENT C2 forming the membrane-bound classical C3 CONVERTASE (C4B2A) and the subsequent C5 CONVERTASE (C4B2A3B) leading to cleavage of COMPLEMENT C5 and the assembly of COMPLEMENT MEMBRANE ATTACK COMPLEX.
Source: MeSH 2007

Complement Pathway, Classical: Related Topics

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Terms associated with Complement Pathway, Classical:

Terms Similar to Complement Pathway, Classical:

Source - MeSH 2007

Broader terms for Complement Pathway, Classical

Source - MeSH 2007

Hierarchical classifications of Complement Pathway, Classical

The following list attempts to classify Complement Pathway, Classical into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

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