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Congenital absence of cerebral hemispheres

Introduction: Congenital absence of cerebral hemispheres

Description of Congenital absence of cerebral hemispheres

Congenital absence of cerebral hemispheres: A congenital condition where the greater portions of the cerebral hemispheres and CORPUS STRIATUM are replaced by CSF and glial tissue. The meninges and the skull are well formed, which is consistent with earlier normal embryogenesis of the telencephalon. Bilateral occlusions of the internal carotid arteries in utero is a potential mechanism. Clinical features include intact brainstem reflexes without evidence of higher cortical activity. (Menkes, Textbook of Child Neurology, 5th ed, p307)
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