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Didanosine

Introduction: Didanosine

Description of Didanosine

Didanosine: A synthetic nucleoside analogue of deoxyadenosine in which the 3' hydroxyl on the ribose moiety is replaced by a hydrogen atom. In vivo, didanosine is converted to the active triphosphate form, which is incorporated into DNA. The absence of the 3' hydroxyl inhibits DNA elongation because phosphodiester bonds cannot be made with the substituted hydrogen. (NCI04)
Source: Diseases Database

Didanosine: A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative active metabolite.
Source: MeSH 2007

Didanosine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Didanosine:

Terms associated with Didanosine:

Terms Similar to Didanosine:

Source: Diseases Database

Source - MeSH 2007

Broader terms for Didanosine

Source - MeSH 2007

The following terms can be used for Didanosine

Source: CRISP

Hierarchical classifications of Didanosine

The following list attempts to classify Didanosine into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

External links related to: Didanosine

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

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  • Subdural empyema
  • Subdural haematoma
  • Subdural haemorrhage
  • Subdural hematoma
  • Subdural hematorrhachis
  • Subdural hemorrhage
  • Subdural hemorrhage following injury without mention of open intracranial wound
  • Subdural hemorrhage following injury, with open intracranial wound
  • Subdural hemorrhage following injury, with open intracranial wound, with brief [less than one hour] loss of consciousness
  • Subdural hemorrhage following injury, with open intracranial wound, with concussion, unspecified
  • Subdural hemorrhage following injury, with open intracranial wound, with loss of consciousness of unspecified duration
  • Subdural hemorrhage following injury, with open intracranial wound, with moderate [1-24 hours] loss of consciousness

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