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Dictionary » DNA Cleavage

DNA Cleavage

Introduction: DNA Cleavage

Description of DNA Cleavage

DNA Cleavage: A reaction that severs one of the covalent sugar-phosphate linkages between NUCLEOTIDES that compose the sugar phosphate backbone of DNA. It is catalyzed enzymatically, chemically or by radiation. Cleavage may be exonucleolytic - removing the end nucleotide, or endonucleolytic - splitting the strand in two.
Source: MeSH 2007

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