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Dictionary » Fibrinoid leukodystrophy

Fibrinoid leukodystrophy

Introduction: Fibrinoid leukodystrophy

Description of Fibrinoid leukodystrophy

Fibrinoid leukodystrophy: A rare inherited disorder of myelin formation. Alexander disease is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of cytoplasmic inclusions called Rosenthal fibers. The fibers contain GLIAL FIBRILLARY ACIDIC PROTEIN in association with ALPHA-CRYSTALLIN B CHAIN. Rosenthal fibers are found predominantly in ASTROCYTES located in the subependymal, subpial, and periventricular areas of the BRAIN.
Source: Diseases Database

Fibrinoid leukodystrophy: Related Topics

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Source: Diseases Database

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