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Fludarabine

Introduction: Fludarabine

Description of Fludarabine

Fludarabine: A fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Administered parenterally as a phosphate salt, fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth. (NCI04)
Source: Diseases Database

Fludarabine: nucleoside analog used alone or in combination with other agents to treat various cancers, especially leukemia.
Source: CRISP

Fludarabine: Related Topics

These medical condition or symptom topics may be relevant to medical information for Fludarabine:

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Fludarabine include:

  • Flumadine

Terms associated with Fludarabine:

Broader terms for Fludarabine

Source - CRISP

The term Fludarabine can be used for:

Source: CRISP

The description of Fludarabine may also be used for the following terms:

Source: CRISP

External links related to: Fludarabine

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

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