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Gastrointestinal stromal tumour

Introduction: Gastrointestinal stromal tumour

Description of Gastrointestinal stromal tumour

Gastrointestinal stromal tumour: Gastrointestinal stromal tumor (GIST) is a mesenchymal neoplasm most commonly seen in the gastrointestinal tract. Cases involving tissues outside the gastrointestinal tract have also been reported (extragastrointestinal gastrointestinal stromal tumor). It is a specific KIT-expressing and KIT-signaling-driven mesenchymal tumor. Until recently, surgery has been the only effective therapy for GIST. However, many patients still experience recurrence. Conventional chemotherapy and radiation therapy have been of limited value. A KIT tyrosine kinase inhibitor, imatinib mesylate (also known as STI-571 or Gleevec), is now effective in the treatment of relapsed and unresectable GIST. - 2003
Source: Diseases Database

Gastrointestinal stromal tumour: Related Topics

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Source: Diseases Database

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