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Dictionary » Hydroxyurea


Introduction: Hydroxyurea

Description of Hydroxyurea

Hydroxyurea: A monohydroxyl-substituted urea (hydroxycarbamate) antimetabolite. Hydroxyurea selectively inhibits ribonucleotide reductase, an enzyme required to convert ribonucleoside diphosphates into deoxyribonucleoside diphosphates, thereby preventing cells from leaving the G1/S phase of the cell cycle. This agent also exhibits radiosensitizing activity by maintaining cells in the radiation-sensitive G1 phase and interfering with DNA repair. (NCI04)
Source: Diseases Database

Hydroxyurea: ribonucleotide reductase inhibitor which thereby lowers intracellular dNTP pools and slows DNA replication and repair; used as antineoplastic, cell devision inhibitor, and possible chemotherapy for sickle cell anemia.
Source: CRISP

Hydroxyurea: An antineoplastic agent that inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.
Source: MeSH 2007

Hydroxyurea: Related Topics

These medical condition or symptom topics may be relevant to medical information for Hydroxyurea:

Drug name confusion

Because many drug names share similar spellings or sound almost identical when spoken, it is possible to mistake the name of a particular medication. Other drugs that are sometimes confused with Hydroxyurea include:

Terms associated with Hydroxyurea:

Terms Similar to Hydroxyurea:

Source: Diseases Database

  • Hydroxycarbamid

Source - MeSH 2007

Broader terms for Hydroxyurea

Source - MeSH 2007

Source - CRISP

Hierarchical classifications of Hydroxyurea

The following list attempts to classify Hydroxyurea into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

External links related to: Hydroxyurea

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

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