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Dictionary » Interleukin-11


Introduction: Interleukin-11

Description of Interleukin-11

Interleukin-11: A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine interleukin 11 (IL-11). Secreted by bone marrow stromal cells and a number of mesenchymal cells, IL-11 binds to and activates its cell-surface receptor, promoting primary and secondary immune responses, modulating antigen-specific antibody reactions, and preventing apoptotic cell death. This agent also stimulates the T-cell-dependent development of IgG-secreting B-cells in spleen cell cultures and may be an important regulator of megakaryocytopoiesis. (NCI04)
Source: Diseases Database

Interleukin-11: cloned from a primate stromal cell line; plays a role in megakaryocyte proliferation and B cell differentiation.
Source: CRISP

Interleukin-11: A lymphohematopoietic cytokine that plays a role in regulating the proliferation of ERYTHROID PROGENITOR CELLS. It induces maturation of MEGAKARYOCYTES which results in increased production of BLOOD PLATELETS. Interleukin-11 was also initially described as an inhibitor of ADIPOGENESIS of cultured preadipocytes.
Source: MeSH 2007

Interleukin-11: Related Topics

These medical condition or symptom topics may be relevant to medical information for Interleukin-11:

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Terms Similar to Interleukin-11:

Source: Diseases Database

Broader terms for Interleukin-11

Source - CRISP

The description of Interleukin-11 may also be used for the following terms:

Source: CRISP

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Source: Diseases Database

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