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Dictionary » Interleukin-2


Introduction: Interleukin-2

Description of Interleukin-2

Interleukin-2: IL-2. A type of biological response modifier (a substance that can improve the body's natural response to infection and disease) that stimulates the growth of certain disease-fighting blood cells in the immune system. These substances are normally produced by the body. Aldesleukin is IL-2 that is made in the laboratory for use in treating cancer and other diseases.
Source: National Institute of Health

Interleukin-2: Encoded by human IL2 Gene, Interleukin-2 is a secreted cytokine important for proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL2 expression in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling expression of a single gene. Targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role in the immune response to antigenic stimuli. (From LocusLink)
Source: Diseases Database

Interleukin-2: interleukin 2 is produced by T cells in response to antigenic or mitogenic stimulation and the signal carried by interleukin1; it stimulates the proliferation of T cells bearing specific receptors for interleukin 2, expressed by antigenically stimulated T cells; it also seems to induce production of interferon gamma, and is used as an anticancer agent in a wide variety of solid malignant tumors.
Source: CRISP

Interleukin-2: A soluble substance elaborated by antigen- or mitogen-stimulated T-LYMPHOCYTES which induces DNA synthesis in naive lymphocytes.
Source: MeSH 2007

Interleukin-2: Related Topics

These medical condition or symptom topics may be relevant to medical information for Interleukin-2:

Terms associated with Interleukin-2:

Terms Similar to Interleukin-2:

Source: Diseases Database

Source - MeSH 2007

Related Topics

Source - MeSH 2007

Broader terms for Interleukin-2

Source - MeSH 2007

Source - CRISP

The term Interleukin-2 can be used for:

Source: CRISP

The description of Interleukin-2 may also be used for the following terms:

Source: CRISP

Hierarchical classifications of Interleukin-2

The following list attempts to classify Interleukin-2 into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

External links related to: Interleukin-2

Source: Diseases Database

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