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Dictionary » Ladakamycin
 

Ladakamycin

Introduction: Ladakamycin

Description of Ladakamycin

Ladakamycin: A pyrimidine nucleoside analogue of cytidine with antineoplastic activity. Azacitidine is incorporated into DNA, where it reversibly inhibits DNA methyltransferase, thereby blocking DNA methylation. Hypomethylation of DNA by azacitidine may activate tumor suppressor genes silenced by hypermethylation, resulting in an antitumor effect. This agent is also incorporated into RNA, thereby disrupting normal RNA function and impairing tRNA cytosine-5-methyltransferase activity. (NCI04)
Source: Diseases Database

Ladakamycin: Related Topics

These medical condition or symptom topics may be relevant to medical information for Ladakamycin:

Terms associated with Ladakamycin:

Terms Similar to Ladakamycin:

Source: Diseases Database

The following terms can be used for Ladakamycin

Source: CRISP

External links related to: Ladakamycin

Source: Diseases Database

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