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Dictionary » Leigh disease

Leigh disease

Introduction: Leigh disease

Description of Leigh disease

Leigh disease (medical condition): A rare, progressive, neurological disorder...more »

See also:

Leigh syndrome:
  »Introduction: Leigh syndrome
  »Symptoms of Leigh syndrome

Leigh disease: A group of metabolic disorders primarily of infancy characterized by the subacute onset of psychomotor retardation, hypotonia, ataxia, weakness, vision loss, eye movement abnormalities, seizures, dysphagia, and lactic acidosis. Pathological features include spongy degeneration of the neuropile of the basal ganglia, thalamus, brain stem, and spinal cord. Patterns of inheritance include X-linked recessive, autosomal recessive, and mitochondrial. Leigh disease has been associated with mutations in genes for the PYRUVATE DEHYDROGENASE COMPLEX; CYTOCHROME-C OXIDASE; ATP synthase subunit 6; and subunits of mitochondrial complex I. (From Menkes, Textbook of Child Neurology, 5th ed, p850).
Source: MeSH 2007

Leigh disease: Related Topics

These medical condition or symptom topics may be relevant to medical information for Leigh disease:

Leigh disease: Rare Disease


Ophanet, a consortium of European partners, currently defines a condition rare when if affects 1 person per 2,000. They list Leigh disease as a "rare disease".

Source - Orphanet

Leigh disease as a Disease

Leigh disease: Another name for Leigh syndrome (or close medical condition association).
  »Introduction: Leigh syndrome
  »Symptoms of Leigh syndrome

Leigh disease: Related Diseases

Leigh disease: Leigh disease is listed as a type of (or associated with) the following medical conditions in our database:

Causes of Leigh disease

Some of the causes of Leigh disease are included in the list below:

Symptoms of Leigh disease (Leigh syndrome)

Some of the symptoms of Leigh disease incude:

Leigh disease: Related Disease Topics

These medical disease topics may be related to Leigh disease:

Terms associated with Leigh disease:

Terms Similar to Leigh disease:

  • Encephalomyelitis, Subacute Necrotizing
  • Encephalopathy, Subacute Necrotizing

Source - MeSH 2007

Related Topics

Source - MeSH 2007

Broader terms for Leigh disease

Source - MeSH 2007

The following terms can be used for Leigh disease

Source: CRISP

Hierarchical classifications of Leigh disease

The following list attempts to classify Leigh disease into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

Interesting Medical Articles:

Medical dictionaries:

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