Have a symptom?
See what questions
a doctor would ask.
Dictionary » Marimastat


Introduction: Marimastat

Description of Marimastat

Marimastat: An orally-active synthetic hydroxamate with potential antineoplastic activity. Marimastat covalently binds to the zinc(II) ion in the active site of matrix metalloproteinases (MMPs), thereby inhibiting the action of MMPs, inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent may also inhibit tumor necrosis factor-alpha converting enzyme (TACE), an enzyme involved in tumor necrosis factor alpha (TNF-alpha) production that may play a role in some malignancies as well as in the development of arthritis and sepsis.(NCI04)
Source: Diseases Database

Marimastat: Related Topics

These medical condition or symptom topics may be relevant to medical information for Marimastat:

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

  • Nasal passage stinging
  • Nasal passage ulcer
  • Nasal pharynx
  • Nasal pits
  • Nasal placodes
  • Nasal point
  • Nasal polyp
  • Nasal polyposis, familial
  • Nasal Polyps
  • Nasal process

    Find out more

    Search to find out more about Marimastat:

    powered by

    By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

    Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise