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Dictionary » Mycophenolate mofetil

Mycophenolate mofetil

Introduction: Mycophenolate mofetil

Description of Mycophenolate mofetil

Mycophenolate mofetil: The morpholinoethyl ester of mycophenolic acid (MPA) with potent immunosuppressive properties. Mycophenolate stops T-cell and B-cell proliferation through selective inhibition of the de novo pathway of purine biosynthesis. In vivo, the active metabolite, MPA, reversibly inhibits inosine 5'-monophosphate dehydrogenase, an enzyme involved in the de novo synthesis of guanine nucleotides. MPA displays high lymphocyte specificity and cytotoxicity due to the higher dependence of activated lymphocytes on both salvage and de novo synthesis of guanine nucleotides relative to other cell types. (NCI04)
Source: Diseases Database

Mycophenolate mofetil: immunosuppressant used in the prophylaxis of organ rejection.
Source: CRISP

Mycophenolate mofetil: Related Topics

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Source: Diseases Database

Source - CRISP

Broader terms for Mycophenolate mofetil

Source - CRISP

The term Mycophenolate mofetil can be used for:

Source: CRISP

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Source: CRISP

External links related to: Mycophenolate mofetil

Source: Diseases Database

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