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Neurofilament protein

Introduction: Neurofilament protein

Description of Neurofilament protein

Neurofilament protein: fibrous protein of the keratin family which accounts for the bulk of neurofilaments.
Source: CRISP

Neurofilament protein: Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in Alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of Alzheimer's patients. (Can J Neurol Sci 1990 Aug;17(3):302).
Source: MeSH 2007

Neurofilament protein: Related Topics

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Broader terms for Neurofilament protein

Source - CRISP

The description of Neurofilament protein may also be used for the following terms:

Source: CRISP

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