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Parathyroid hormone-related protein: calcium-regulating hormone with endocrine, paracrine, and autocrine actions in bone; can cause hypercalcemia.
Parathyroid hormone-related protein: A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.
Source: MeSH 2007
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