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Phorbol 12,13-Dibutyrate: A phorbol ester found in $CROTON OIL$ which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems.
Source: MeSH 2007
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