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Properdin

Introduction: Properdin

Description of Properdin

Properdin: a non-immunoglobulin, gammaglobulin complement of the alternative pathway; it complexes with C3b and stabilizes alternative pathway C3 convertase.
Source: CRISP

Properdin: A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.
Source: MeSH 2007

Properdin: Related Topics

These medical condition or symptom topics may be relevant to medical information for Properdin:

Terms associated with Properdin:

Terms Similar to Properdin:

  • Complement Factor P

Source - MeSH 2007

Broader terms for Properdin

Source - MeSH 2007

Source - CRISP

Other terms that may be related to Properdin:

Source: CRISP

The description of Properdin may also be used for the following terms:

Source: CRISP

Hierarchical classifications of Properdin

The following list attempts to classify Properdin into categories where each line is subset of the next.

MeSH 2007 Hierarchy:

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

MeSH 2007 Hierarchy

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

  • Precipitin
  • Precipitin reaction
  • Precipitin test
  • Precipitinogen
  • Precipitinogenoid
  • Precipitogen
  • Precipitoid
  • Precipitophore
  • Precipitous drop in hematocrit
  • Precision

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