Have a symptom?
See what questions
a doctor would ask.
Dictionary » Pseudohypoparathyroidism type 1a

Pseudohypoparathyroidism type 1a

Introduction: Pseudohypoparathyroidism type 1a

Description of Pseudohypoparathyroidism type 1a

Pseudohypoparathyroidism type 1a: Originally reported as a hypocalcemic syndrome similar to hypoparathyroidism, but with renal and skeletal resistance to parathyroid hormone (PTH) and designated as "pseudohypoparathyroidism." Albright later defined a normocalcemic variant which he termed "pseudopseudohypoparathyroidism." Two separate forms of pseudohypoparathyroidism are recognized. Type I in which there is no increase in the urinary excretion of cyclic adenosine monophosphate (cAMP) and phosphate in response to parathyroid hormone (PTH). Type II in which there is a response to PTH, but without phosphate diuresis. The erythrocytes of some patients with type I contain a defective receptor-cyclase coupling protein (stimulatory guanine nucleoside-binding protein, or GS) which is responsible for coupling the cellular receptor that binds parathyroid hormone (PTH) and is involved with the formation and release of cyclic adenosine monophosphate (cAMP). This variant has been designated as "pseudohypoparathyroidism type Ia." The syndrome is associated with mental deficiency, dystrophic bone lesions, short stature, and other defects.
Source: Diseases Database

Pseudohypoparathyroidism type 1a: Related Topics

These medical condition or symptom topics may be relevant to medical information for Pseudohypoparathyroidism type 1a:

Terms associated with Pseudohypoparathyroidism type 1a:

Terms Similar to Pseudohypoparathyroidism type 1a:

Source: Diseases Database

External links related to: Pseudohypoparathyroidism type 1a

Source: Diseases Database

Interesting Medical Articles:

Medical dictionaries:

More Medical Dictionary Topics

  • Loose body in joint of pelvic region and thigh
  • Loose body in joint of shoulder region
  • Loose body in joint, site unspecified
  • Loose body in knee
  • Loose body in upper arm joint
  • Loose bowel motions
  • Loose cartilage
  • Loose connective tissue of abdomen
  • Loose connective tissue of subcutaneous tissue
  • Loose skin
  • Loose stool

    Find out more

    Search to find out more about Pseudohypoparathyroidism type 1a:

    powered by

    By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

    Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise