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Dictionary » Raloxifene


Introduction: Raloxifene

Description of Raloxifene

Raloxifene: A drug that belongs to the family of drugs called selective estrogen receptor modulators (SERMs) and is used in the prevention of osteoporosis in postmenopausal women. Raloxifene is also being studied as a cancer prevention drug.
Source: National Institute of Health

Raloxifene: A selective benzothiophene estrogen receptor modulator (SERM). Raloxifene binds to and interacts with estrogen receptors (ER) as a mixed estrogen agonist/antagonist; it displays both an ER-alpha-selective partial agonist/antagonist effect and a pure ER-beta-selective antagonist effect. This agent functions as an estrogen agonist in some tissues (bones, lipid metabolism) and as an estrogen antagonist in others (endometrium and breasts), with the potential for producing some of estrogen's beneficial effects without producing its adverse effects. In postmenopausal women, raloxifene may reduce the risk of strokes, osteoporosis and breast cancer. (NCI04)
Source: Diseases Database

Raloxifene: a selective estrogen receptor modulator; has both agonist and antagonist estrogen action.
Source: CRISP

Raloxifene: A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
Source: MeSH 2007

Raloxifene: Related Topics

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Broader terms for Raloxifene

Source - CRISP

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Source: CRISP

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Source: Diseases Database

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