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RNA-Induced Silencing Complex: A multicomponent, ribonucleoprotein complex that cleaves specific mRNAs (RNA, MESSENGER) which are targeted for degradation by homologous dsRNAs (RNA, DOUBLE-STRANDED) during the process of RNA INTERFERENCE. It includes siRNA (RNA, SMALL INTERFERING) that is generated from the specific dsRNA.
Source: MeSH 2007
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