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Dictionary » Stavudine


Introduction: Stavudine

Description of Stavudine

Stavudine: A synthetic nucleoside, analog of didehydro-3-deoxythymidine with potent antiretroviral activity. In vivo, stavudine is phosphorylated by cellular kinases to the active metabolite stavudine triphosphate; this metabolite inhibits the activity of HIV reverse transcriptase both by competing with the natural substrate deoxythymidine triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack the essential 3'-OH group). (NCI04)
Source: Diseases Database

Stavudine: nucleoside analog; used as an antiviral agent.
Source: CRISP

Stavudine: A dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.
Source: MeSH 2007

Stavudine: Related Topics

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Terms Similar to Stavudine:

Source: Diseases Database

Source - CRISP

Broader terms for Stavudine

Source - CRISP

The term Stavudine can be used for:

Source: CRISP

Other terms that may be related to Stavudine:

Source: CRISP

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Source: Diseases Database

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