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Dictionary » Superantigen


Introduction: Superantigen

Description of Superantigen

Superantigen: class of bacterial and viral proteins which stimulate a large proportion of T lymphocytes based on the expression of specific T cell antigen receptor Vbeta elements and thus do not require antigen processing by MHC class II molecules.
Source: CRISP

Superantigen: Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.
Source: MeSH 2007

Superantigen: Related Topics

These medical condition or symptom topics may be relevant to medical information for Superantigen:

Terms associated with Superantigen:

Broader terms for Superantigen

Source - CRISP

Other terms that may be related to Superantigen:

Source: CRISP

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