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Dictionary » Thyroid Hormone Resistance Syndrome

Thyroid Hormone Resistance Syndrome

Introduction: Thyroid Hormone Resistance Syndrome

Description of Thyroid Hormone Resistance Syndrome

Thyroid Hormone Resistance Syndrome: An inherited autosomal recessive trait, characterized by peripheral resistance to THYROID HORMONES and the resulting elevation in serum levels of THYROXINE and TRIIODOTHYRONINE. This syndrome is caused by mutations of gene THRB encoding the THYROID HORMONE RECEPTORS BETA in target cells. HYPOTHYROIDISM in these patients is partly overcome by the increased thyroid hormone levels.
Source: MeSH 2007

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