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Dictionary » Wiskott-Aldrich Syndrome Protein Family

Wiskott-Aldrich Syndrome Protein Family

Introduction: Wiskott-Aldrich Syndrome Protein Family

Description of Wiskott-Aldrich Syndrome Protein Family

Wiskott-Aldrich Syndrome Protein Family: A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.
Source: MeSH 2007

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