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Causes of Neuronal Migration Disorders

Causes of Neuronal Migration Disorders

Neuronal migration disorders are a group of birth defects caused by abnormal movement of the neurons during fetal brain and nervous system development. The underlying cause in many cases is genetic.

Neuronal Migration Disorders: Related Medical Conditions

To research the causes of Neuronal Migration Disorders, consider researching the causes of these these diseases that may be similar, or associated with Neuronal Migration Disorders:

Neuronal Migration Disorders: Causes and Types

Causes of Types of Neuronal Migration Disorders: Review the cause informationfor the various types of Neuronal Migration Disorders:

Causes of Broader Categories of Neuronal Migration Disorders: Review the causal information about the various more general categories of medical conditions:

What causes Neuronal Migration Disorders?

Article excerpts about the causes of Neuronal Migration Disorders:
NMDs may be caused by genetic or biochemical abnormalities (e.g., Zellweger syndrome). Several genetic abnormalities have been identified, including a deletion of a gene on chromosome 17p13.3—which causes lissencephaly—and a mutation of a gene on chromosome Xq22.3,which causes lissencephaly in males and band heterotopia in females. The Reelin gene on chromosome 7q22 causes microcephaly, lissencephaly, cerebellar hypoplasia (small cerebellum), and lymphedema. Abnormalities on a number of other genes have been identified as the cause of NMDs, yet their roles in neuronal migration are not well-understood. (Source: excerpt from NINDS Neuronal Migration Disorders Information Page: NINDS)

Related information on causes of Neuronal Migration Disorders:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of Neuronal Migration Disorders may be found in:

 

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