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Improved immunosuppressants for transplant recipients

Bone marrow transplants are a last resort therapy for treating such diseases as blood cancers and genetic blood disorders. It provides the recipient with all types of blood cells including red and white blood cells. Bone marrow recipients are normally required to have toxic drugs to destroy their immune system before undergoing a bone marrow transplant. A new technique that isolates one subset of the recipients' immune system has been developed to prevent the fatal graft versus host disease (GVHD) following the transplant. Antigen-presenting cells (APCs) are a primary factor in causing GVHD and continue to circulate in the blood after immune destroying drugs have obliterated the bone marrow. By targeting these cells scientists have successfully prevented GVHD in study subjects.

Source: summary of medical news story as reported by Medical News Today

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About: Improved immunosuppressants for transplant recipients

Date: 17 July 2005

Source: Medical News Today

Author: Franklin Hoke


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