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Two variations of a gene (ESR1) may predispose women to breast cancer claim US researchers. These gene mutations are two of several other mutations (BRCA1, BRCA2 and p53) that are linked to breast cancer. It has also been discovered that three genetic variations in the ESR1 gene have a protective effect against breast cancer. It is believed that the genetic variations may affect estrogen receptor pathways which presents the opportunity to develop treatments that alter the effect of estrogen on breast cancer cells.
Source: summary of medical news story as reported by Reuters
About: Researchers discover new gene variations that increase breast cancer risk
Date: 15 December 2004
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