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Research has shown new evidence how COX-2 inhibitors, i.e. Vioxx and Celebrex, increase the risk of heart attacks and strokes in models. They inhibit the body's production of prostacyclin, a protective hormone that changes the stretch of the blood vessel in response to changes in blood pressure. This inhibition increases the development of atherosclerosis, fatty plaques on the blood vessel walls. Further understanding of how the drugs work is hoped to allow their safe usage in future practice.
Source: summary of medical news story as reported by AScribe Newswire
About: Scientific models explain Cox-2 inhibitor risks
Date: 24 May 2005
Source: AScribe Newswire
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