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Triiodothyronine: A therapeutic formulation of the primary physiologically active form of endogenous thyroid hormone. In vivo, triiodothyronine enters the nucleus and binds to nuclear thyroid hormone receptors that subsequently bind to thyroid response elements (TREs) located in target genes. Receptor binding by triiodothyronine in combination with recruited coactivators results in maximal transcriptional activation after binding to TREs; in general, binding of thyroid hormone receptor alone to TREs leads to repression of gene transcription (NCI04)
Source: Diseases Database
Triiodothyronine : one of the thyroid hormones; an organic iodine containing compound secreted in small amounts by the thyroid gland; most circulating triiodothyroinine is produced by the deiodination of thyroxine in the peripheral tissues.
Triiodothyronine: Triiodothyronine is one of the thyroid hormones, chemical substances that play a big role in regulating many of the body's processes. Triiodothyronine is important to proper protein synthesis, development of all the body's cells, and bone growth. It also regulates metabolism and energy production and body temperature. Iodine is vital to the normal production of triiodothyronine, which is secreted by the thyroid epithelial cells. Its secretion is controlled by thyroid-stimulating hormone.
Conditions that can afflict triiodothyronine include hypothyroidism, hyperthyroidism, thyroid cancer, thyroid nodules, iodine deficiency, goiter, Grave's disease, trauma, and hypopituitarism.
The following organs are closely related to the organ: Triiodothyronine:
The following conditions are related to the organ: Triiodothyronine:
The following are other names for the organ: Triiodothyronine:
These symptoms are related to afflictions of the organ: Triiodothyronine:
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