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Diseases » Parkinson's Disease » Inheritance

Inheritance and Genetics of Parkinson's Disease

Parkinson's Disease: Genetics Information

Genetics of Parkinson's Disease: Until relatively recently, Parkinson disease was not though to be heritable, and research was primarily focused on environmental risk factors such as viral infection or neurotoxins. However, a positive family history was gradually perceived to be a risk factor, a view that was confirmed last year when a candidate gene for some cases of Parkinson disease was mapped to chromosome 4. Mutations in this gene have now been linked to several Parkinson disease families. The product of this gene, a protein called alpha-synuclein, is a familiar culprit: a fragment of it is a known constituent of Alzheimer disease plaques. (Source: Genes and Disease by the National Center for Biotechnology)

About inheritance and genetics:

Inheritance of Parkinson's Disease refers to whether the condition is inherited from your parents or "runs" in families. The level of inheritance of a condition depends on how important genetics are to the disease. Strongly genetic diseases are usually inherited, partially genetic diseases are sometimes inherited, and non-genetic diseases are not inherited. For general information, see Introduction to Genetics.


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