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Diseases » PFIC » Introduction


PFIC: Introduction

PFIC: A rare inherited condition where bile is unable to drain from the liver where it builds up and causes progressive liver damage. End-stage liver disease usually occurs before adulthood. There are three different subtypes of the disorder, each with a different genetic origin of the defect. More detailed information about the symptoms, causes, and treatments of PFIC is available below.

Symptoms of PFIC

Treatments for PFIC

  • Dietary management - Diet should be high in carbohydrates and protein. Supplementation of fat soluble vitamins is necessary
  • Medical treatment
    • Ursodeoxycholic acid - may be tried but most forms of the disease do not respond to medical treatment
  • Surgical treatment
    • Diversion of bile salts from the enterohepatic circulation - cutaneous diversion, ileal diversion. May result in resolution of liver disease in most patients
  • more treatments...»

Home Diagnostic Testing

Home medical testing related to PFIC:

Wrongly Diagnosed with PFIC?

PFIC: Complications

Review possible medical complications related to PFIC:

Causes of PFIC

Read more about causes of PFIC.

Misdiagnosis and PFIC

Chronic liver disease often undiagnosed: One study reported that 50% of patients with a chronic liver disease remain undiagnosed by their primary physician. The reasons more »

PFIC: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

PFIC: Animations

Statistics for PFIC

PFIC: Broader Related Topics

User Interactive Forums

Read about other experiences, ask a question about PFIC, or answer someone else's question, on our message boards:

Definitions of PFIC:

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list PFIC as a "rare disease".
Source - Orphanet


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