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SAPHO syndrome

SAPHO syndrome: Introduction

SAPHO syndrome: A rare disorder involving skin (acne, pustulosis), bone (hyperostosis, osteitis) and joint problems. More detailed information about the symptoms, causes, and treatments of SAPHO syndrome is available below.

Symptoms of SAPHO syndrome

Wrongly Diagnosed with SAPHO syndrome?

SAPHO syndrome: Related Patient Stories

SAPHO syndrome: Complications

Read more about complications of SAPHO syndrome.

Causes of SAPHO syndrome

Read more about causes of SAPHO syndrome.

Misdiagnosis and SAPHO syndrome

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SAPHO syndrome: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

Evidence Based Medicine Research for SAPHO syndrome

Medical research articles related to SAPHO syndrome include:

Click here to find more evidence-based articles on the TRIP Database

SAPHO syndrome: Animations

Prognosis for SAPHO syndrome

Prognosis for SAPHO syndrome: prolonged unpredictable course

Research about SAPHO syndrome

Visit our research pages for current research about SAPHO syndrome treatments.

Statistics for SAPHO syndrome

SAPHO syndrome: Broader Related Topics

User Interactive Forums

Read about other experiences, ask a question about SAPHO syndrome, or answer someone else's question, on our message boards:

Definitions of SAPHO syndrome:

Syndrome consisting of synovitis, acne, palmoplantar pustulosis, hyperostosis, and osteitis (SAPHO). The most common site of the disease is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions, hyperostosis, and arthritis of the adjacent joints. The association of sterile inflammatory bone lesions and neutrophilic skin eruptions is indicative of this syndrome. - (Source - Diseases Database)

SAPHO syndrome is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that SAPHO syndrome, or a subtype of SAPHO syndrome, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)

Ophanet, a consortium of European partners, currently defines a condition rare when it affects 1 person per 2,000. They list SAPHO syndrome as a "rare disease".
Source - Orphanet


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