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Diseases » SCID » Introduction


SCID: Introduction

SCID: Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders characterized by little or no immune response. The defining ... more about SCID.

SCID: Major failure of the immune system, usually genetic. More detailed information about the symptoms, causes, and treatments of SCID is available below.

Symptoms of SCID

Treatments for SCID

Home Diagnostic Testing

Home medical testing related to SCID:

Wrongly Diagnosed with SCID?

SCID: Related Patient Stories

SCID: Deaths

Read more about Deaths and SCID.

Types of SCID

  • SCID with ADA deficiency - X-linked common type
  • SCID from IL-2 receptor gamma chain deficiency - X-linked common type
  • X-linked SCID
  • MHC Class II Deficiency (Bare Lymphocyte Syndrome)
  • DiGeorge syndrome
  • more types...»

Diagnostic Tests for SCID

Test for SCID in your own home

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SCID: Complications

Review possible medical complications related to SCID:

Causes of SCID

Read more about causes of SCID.

Disease Topics Related To SCID

Research the causes of these diseases that are similar to, or related to, SCID:

Less Common Symptoms of SCID

SCID: Undiagnosed Conditions

Commonly undiagnosed diseases in related medical categories:

SCID: Research Doctors & Specialists

Research related physicians and medical specialists:

Other doctor, physician and specialist research services:

Hospitals & Clinics: SCID

Research quality ratings and patient safety measures for medical facilities in specialties related to SCID:

Choosing the Best Hospital: More general information, not necessarily in relation to SCID, on hospital performance and surgical care quality:

Research about SCID

Visit our research pages for current research about SCID treatments.

Clinical Trials for SCID

The US based website lists information on both federally and privately supported clinical trials using human volunteers.

Some of the clinical trials listed on for SCID include:

Statistics for SCID

SCID: Broader Related Topics

SCID Message Boards

Related forums and medical stories:

User Interactive Forums

Read about other experiences, ask a question about SCID, or answer someone else's question, on our message boards:

Article Excerpts about SCID

Genes and Disease by the National Center for Biotechnology (Excerpt)

Severe combined immunodeficiency (SCID) represents a group of rare, sometimes fatal, congenital disorders characterized by little or no immune response. The defining feature of SCID, commonly known as "bubble boy" disease, is a defect in the specialized white blood cells (B- and T-lymphocytes) that defend us from infection by viruses, bacteria and fungi. (Source: Genes and Disease by the National Center for Biotechnology)

Primary Immune Deficiency, NIAID Fact Sheet: NIAID (Excerpt)

Approximately one in every million people develop SCID, a group of inherited disorders. People with SCID have severe abnormalities in both B and T cell immunity. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Definitions of SCID:

X-linked or autosomal recessive disorder characterized by defects of both humoral and cell mediated immunity, resulting in low or absent antibody levels, leukopenia, marked susceptibility to infections, and early death.--2004 - (Source - Diseases Database)

A congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life - (Source - WordNet 2.1)

SCID is listed as a "rare disease" by the Office of Rare Diseases (ORD) of the National Institutes of Health (NIH). This means that SCID, or a subtype of SCID, affects less than 200,000 people in the US population.
Source - National Institutes of Health (NIH)


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