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Symptoms of Selective IgA Deficiency

Symptoms of Selective IgA Deficiency

The list of signs and symptoms mentioned in various sources for Selective IgA Deficiency includes the 12 symptoms listed below:

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Selective IgA Deficiency: Complications

Review medical complications possibly associated with Selective IgA Deficiency:

Diagnostic Testing

Diagnostic testing of medical conditions related to Selective IgA Deficiency:

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Do I have Selective IgA Deficiency?

Wrongly Diagnosed with Selective IgA Deficiency?

The list of other diseases or medical conditions that may be on the differential diagnosis list of alternative diagnoses for Selective IgA Deficiency includes:

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More information about symptoms of Selective IgA Deficiency and related conditions:

Other Possible Causes of these Symptoms

Click on any of the symptoms below to see a full list of other causes including diseases, medical conditions, toxins, drug interactions, or drug side effect causes of that symptom.

Article Excerpts About Symptoms of Selective IgA Deficiency:

Many IgA-deficient patients are healthy, with no more than the usual number of infections. Those patients who do have symptoms typically have recurring ear, sinus, or lung infections that may not respond to standard courses of antibiotics. People with IgA-deficiency are likely to have other problems, including allergies, asthma, chronic diarrhea, and autoimmune diseases.

How is IgA deficiency diagnosed?

People with IgA deficiency have low levels of IgA antibodies in their blood. In contrast, their levels of IgM and IgG immunoglobulins usually are normal. IgA-deficient people also have normal levels of other immune system cells, including T cells, phagocytes, and complement proteins.

Doctors diagnose IgA deficiency by doing tests to measure the amount of total immunoglobulin in the blood as well as the type of immunoglobulin known as IgG2. Other tests determine how well a person is producing antibodies against specific germs following immunization with a common vaccine, such as a tetanus shot.

What causes IgA deficiency?

IgA deficiency is caused by faulty white blood cells called B cells or B lymphocytes. While patients have normal numbers of B cells, these cells do not mature into normal IgA-producing cells. Scientists do not yet know the exact cause or causes for these immature B cells. Sometimes clusters of cases occur in families, and IgA-deficient patients are more likely than the general population to be related to someone with combined variable immunodeficiency, another form of immunodeficiency discussed below. Research is underway to determine the location of the suspected genes on the involved chromosomes.

How is IgA deficiency treated?

There is no specific treatment for selective IgA deficiency. Doctors treat bacterial infections with antibiotics, and patients with giardiasis (an infection caused by a common intestinal parasite receive metronidazole or quinacrine hydrochloride. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Medical articles and books on symptoms:

These general reference articles may be of interest in relation to medical signs and symptoms of disease in general:

About signs and symptoms of Selective IgA Deficiency:

The symptom information on this page attempts to provide a list of some possible signs and symptoms of Selective IgA Deficiency. This signs and symptoms information for Selective IgA Deficiency has been gathered from various sources, may not be fully accurate, and may not be the full list of Selective IgA Deficiency signs or Selective IgA Deficiency symptoms. Furthermore, signs and symptoms of Selective IgA Deficiency may vary on an individual basis for each patient. Only your doctor can provide adequate diagnosis of any signs or symptoms and whether they are indeed Selective IgA Deficiency symptoms.


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