Associated Conditions for Sjogren's Syndrome
Excerpts on associated medical conditions for Sjogren's Syndrome:
Connective tissue is the framework of the body that
supports organs and tissues. Examples are joints, muscles, bones, skin,
blood vessel walls, and the lining of internal organs. Many connective
tissue disorders are autoimmune diseases, and several are common among
people with Sjögren's:
Polymyositis is an inflammation of the muscles
that causes weakness and pain, difficulty moving, and, in some cases,
problems breathing and swallowing. If the skin is inflamed too, it's
called dermatomyositis. The disease is treated with corticosteroids
In Raynaud's phenomenon, blood vessels in the
hands, arms, feet, and legs constrict (narrow) when exposed to cold.
The result is pain, tingling, and numbness. When vessels constrict,
fingers turn white. Shortly after that, they turn blue because of
blood that remained in the tissue pools. When new blood rushes in, the
fingers turn red. The problem is treated with medicines that dilate
blood vessels. Raynaud's phenomenon usually occurs before dryness of
the eyes or mouth.
Rheumatoid arthritis (RA) is severe inflammation
of the joints that can eventually deform the surrounding bones
(fingers, hands, knees, etc.). RA can also damage muscles, blood
vessels, and major organs. Treatment depends on the severity of the
pain and swelling and which body parts are involved. It may include
physical therapy, aspirin, rest, nonsteroidal anti-inflammatory
agents, steroids, or immunosuppressants.
Scleroderma causes the body to accumulate too
much collagen, a protein commonly found in the skin. The result is
thick, tight skin and damage to muscles, joints, and internal organs
such as the esophagus, intestines, lungs, heart, kidneys, and blood
vessels. Treatment is aimed at relieving pain and includes drugs, skin
softeners, and physical therapy.
Systemic lupus erythematosus (SLE) causes joint
and muscle pain, weakness, skin rashes, and, in more severe cases,
heart, lung, kidney, and nervous system problems. As with RA,
treatment for SLE depends on the symptoms and may include aspirin,
rest, steroids, and anti-inflammatory and other drugs, as well as
dialysis and high blood pressure medicine.
Vasculitis is an inflammation of the blood
vessels, which then become scarred and too narrow for blood to get
through to reach the organs. In people with Sjögren's, vasculitis
tends to occur in those who also have Raynaud's phenomenon and lung
and liver problems.
Autoimmune thyroid disorders are common with
Sjögren's. They can appear as either the overactive thyroid of Graves'
disease or the underactive thyroid of Hashimoto's. Nearly half of the
people with autoimmune thyroid disorder also have Sjögren's, and many
people with Sjögren's show evidence of thyroid disease.
(Source: excerpt from Questions and Answers About Sjögren's Syndrome: NIAMS
List of associated medical conditions for Sjogren's Syndrome:
The list of conditions mentioned by various sources
as associated with Sjogren's Syndrome includes:
Sjogren's Syndrome as a risk factor:
Another type of associated condition is one for which Sjogren's Syndrome
is itself a risk factor. The conditions for which Sjogren's Syndrome is listed as a risk
About associated conditions for Sjogren's Syndrome:
Associated conditions are those which appear
statistically related, but do not have
a clear cause or effect relationship.
Whereas the complications
are caused by Sjogren's Syndrome,
and underlying causes
may be causes of Sjogren's Syndrome,
the following list shows associated conditions
that simply appear with higher frequency in people
who have Sjogren's Syndrome.
In some cases, there may be overlap
between this list and risk factors
for Sjogren's Syndrome.
People with Sjogren's Syndrome may be more likely to
get a condition on the list of associated conditions,
or the reverse may be true, or both.
Whether they are causes of, caused by, or simply
coincidentally related to Sjogren's Syndrome
is not always clear.
For general information,
see Associated Condition Misdiagnosis.