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Symptoms » Nail symptoms » Glossary
 

Glossary for Nail symptoms

Medical terms related to Nail symptoms or mentioned in this section include:

  • Abscess: This is an area of puss collected in a cavity which is constituted by necrotised tissue
  • Acanthokeratodermia: An uncommon skin condition involving excessive growth of the horny part of the skin on the palms of the hands and soles of the feet. Patients also suffer thickening of the nails.
  • Achrestic anemia: Achrestic anemia is a form of anemia similar to that caused by Vitamin B12 deficiency but it doesn't respond to treatment with Vitamin B12. The condition tends to progress slowly and can result in death if not treated. There are a variety of possible causes.
  • Acrofacial dysostosis, Weyers type: A rare disorder characterized by facial abnormalities and extra digits, nail abnormalities and short limbs.
  • Acroosteolysis neurogenic: A very rare inherited condition characterized mainly by the loss of all sensations - the lose the ability to feel pain, temperature and touch. The loss of sensation generally starts at the toes and fingers and spreads up the limbs and the trunk may also be involved in some cases.
  • Acute paronychia:
  • Alopecia Areata: A condition where hair loss occurs in patches for unknown reasons. Although the condition often disappears within a year, it often reoccurs.
  • Alves Castelo dos Santos syndrome: A rare syndrome characterized by hair, eye, skin and spinal abnormalities.
  • Amelo-onycho-hypohidrotic syndrome: A rare disorder characterized primarily by tooth and nail abnormalities and reduced sweating ability.
  • Anemia: Reduced red blood cells in the blood
  • Anemia, Iron-Deficiency: A lack of fully functioning red blood cells due to a deficiency of iron. The iron allows the body to make hemoglobin in red blood cells which in turn allows the red blood cell to carry oxygen.
  • Anemia, hypochromic microcytic: A blood disorder where red blood cells are too small and lack sufficient iron. It can be inherited or caused by insufficient iron in the diet or from a genetic disorder.
  • Anonychia -- ectrodactyly: A very rare syndrome characterized by the absence of nails and the absence of all or part of one or more fingers or toes (ectrodactyly).
  • Anonychia -- microcephaly: A very rare syndrome characterized by the absence of nails and a small head.
  • Anonychia -- onychodystrophy: A rare birth malformation characterized by absent nails and dystrophic nails.
  • Anonychia onychodystrophy brachydactyly type b: A rare, dominantly inherited disorder characterized abnormal or absent nails, permanently flexed fingers and a broad, finger-like thumb.
  • Anonychia-onychodystrophy with brachydactyly type B and ectrodactyly: A rare, dominantly inherited disorder characterized abnormal or absent nails, missing fingers, permanently flexed fingers and a broad, finger-like thumb.
  • Antley-Bixler Syndrome: A rare genetic disorder characterized by premature closing of skull bones, choanal atresia and craniofacial and limb abnormalities.
  • Antley-Bixler-like syndrome -- ambiguous genitalia -- disordered steroidogenesis: A rare genetic disorder involving a deficiency of an enzyme (cytochrome P450 oxidoreductase) which causes steroid abnormalities. The condition results in ambiguous genitalia in females due to excessive androgen during fetal growth. Patients can also have the bone symptoms of Antley-Bixler syndrome.
  • Anxiety: Excessive worry, anxiety, or fear.
  • Aplasia/hypoplasia of pelvis, femur, fibula, and ulna with abnormal digits and nails: A rare syndrome characterized by the underdevelopment or absence of the pelvis, thigh bone, shin bone and ulna (forearm bone) as well as digital and nail abnormalities.
  • Arm symptoms: Symptoms affecting the arm
  • Arteriosclerosis: A group of medical conditions which are characterized by the thickening and loss of elasticity of arterial blood vessel walls
  • Asphyxiating Thoracic Dystrophy: A rare genetic disorder characterized by short limbs, underdeveloped iliac wings and a narrow rigid thoracic cage that often results in asphyxiation.
  • Athabaskan severe combined immunodeficiency: A severe immunodeficiency disorder found in Navajo and Apache populations.
  • Athlete's foot: A condition which is characterized by a chronic superificial infection of the foot caused by a fungi
  • Baughman syndrome: A rare syndrome characterized mainly by fused eyelids, curly hair and abnormal nails.
  • Beau's lines: Beau's lines are grooves or depressions that run across the nail.
  • Biemond syndrome type 3: A rare inherited condition characterized by the inability to feel pain as well as other anomalies.
  • Blue nails: A condition which is characterized by the occurrence of nails that are blue in appearance
  • Blue nails in children: Blue nails in children, sometimes called cyanosis, occurs due to extreme cold, a lack of oxygen in the cells of the skin under the nails, and other causes in children.
  • Brachydactyly type B: A form of finger deformity characterized by absent or underdeveloped end and middle bones of fingers and toes as well as absent or underdeveloped nails.
  • Brachydactyly, type A5, nail dysplasia: A rare digital anomaly where the middle bones of the second to fifth fingers are missing and the nails are abnormal.
  • Brittle fingernails: A condition which is characterized by brittle fingernails
  • Brittle nails: thinning of the nail plate
  • Brittle nails in children: Brittle nails in children are fingernails or toenails in a child that are dry and break easily.
  • Brown arcs under the nail margins: brown line under the nails is seen in
  • Brown nails: The occurrence of brown nails
  • Brown nails in children: Brown nails in children occur when a child's nails are brown colored.
  • Bullous dystrophy, macular type: A rare condition characterized by loss of scalp hair, increased skin pigmentation, small head, mental retardation, short stature and blisters. The blisters do not form necessarily on skin that has suffered trauma but occurs spontaneously.
  • COPD: Severe obstruction of bronchial air flow typically from bronchitis and/or emphysema.
  • Cancer: Abnormal overgrowth of body cells.
  • Cataract and congenital ichthyosis: A rare syndrome characterized by the presence of cataracts and a dry, scaly skin condition (ichthyosis) at birth or soon after.
  • Cataract, alopecia, sclerodactyly: A rare disorder characterized by cataracts, lack of hair and skin changes in the hands and feet.
  • Chemical pneumonia: Lung inflammation from inhaled chemicals
  • Chitayat Meunier Hodgkinson syndrome: A very rare syndrome characterized by face and finger abnormalities
  • Chloramphenicol-induced Sideroblastic anemia: Chloramphenicol-induced sideroblastic anemia is a blood disorder caused by taking a drug called chloramphenicol. The body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Chondroectodermal dysplasia: An inherited skeletal dysplasia marked that results in short-limbed dwarfism, development of an extra finger as well as cardiovascular impairments. Also called Ellis-van Creveld syndrome.
  • Christianson Fourie syndrome: A very rare syndrome characterized mainly by hair and nail abnormalities.
  • Chromosome 10p terminal deletion syndrome: A very rare syndrome caused by a chromosomal defect (10p terminal deletion) and can result in a variety of malformations that are similar to DiGeorge syndrome and velocardiofacial syndrome.
  • Chromosome 19p duplication syndrome: A rare chromosomal disorder where the short arm of chromosome 19 is duplicated resulting in various abnormalities.
  • Chromosome 19q13.11 Deletion syndrome: A rare genetic syndrome involving features such as poor fetal growth, reduced fetal activity, developmental problems and various other physical symptoms.
  • Chromosome 21, tetrasomy 21q: A rare chromosomal disorder where there is four copies of the long arm of chromosome 21 instead of the normal two which results in various physical and mental anomalies.
  • Chromosome 22 trisomy mosaic: A rare chromosomal disorder where three copies of chromosome 22 are present in some of the body's cells instead of the normal two. Severity of symptoms is determined by how many cells have the extra chromosomal material.
  • Chromosome 22, trisomy: A very rare disorder where there is an extra copy of chromosome 22 in all the body cells. The condition is usually fatal soon after birth or during the fetal stage.
  • Chromosome 3, trisomy 3q: A rare chromosomal disorder where a portion of the long arm (q) of chromosome 3 is duplicated so there is three copies of it rather than the normal two. The condition is characterized by mental and growth deficiency, broad nose root and excessive hair growth.
  • Chromosome 5, trisomy 5q: A rare chromosomal disorder involving duplication of the long arm (q) of chromosome 5 which results in various abnormalities depending on the size and location of the portion of duplicated genetic material.
  • Chromosome 5q duplication syndrome: A rare chromosomal disorder involving duplication of the long arm (q) of chromosome 5 which results in various abnormalities depending on the size and location of the portion of duplicated genetic material.
  • Chromosome 8, monosomy 8p: A rare chromosomal disorder involving deletion of genetic material from the short arm (p) of chromosome 8 resulting in various abnormalities. The type and severity of symptoms varies depending on the amount and exact location of the genetic material that is deleted.
  • Chromosome 8p inverted duplication syndrome: A rare chromosomal disorder involving the inverted duplication of the short arm (p) of chromosome 8 resulting in three copies of the genetic material instead of the normal two. The type and severity of symptoms is determined by the location and size of the duplication.
  • Chromosome 9 trisomy syndrome: A rare chromosomal disorder where there are three copies of chromosome 9 in the body's cells instead of the normal two resulting in various abnormalities.
  • Chromosome 9, trisomy: A rare chromosomal disorder where there are three copies of chromosome 9 in the body's cells instead of the normal two resulting in various abnormalities. The type and severity of symptoms varies depending on the amount and exact location of the genetic material that is duplicated.
  • Chronic infections: Ongoing and often slow progressing infection; opposite to acute infections.
  • Chronic paronychia:
  • Clouston syndrome: A rare genetic ectodermal disorder characterized by skin, hair, nail and eye abnormalities.
  • Conditions associated with nail abnormalities: Nail abnormalities are problems with the color, shape, texture, or thickness of the fingernails or toenails.
  • Congenital heart defects: Heart defects that a baby is born with.
  • Congenital heart disease: Diseases of the heart that one is born with
  • Copper deficiency-induced Sideroblastic anemia: Copper deficiency-induced sideroblastic anemia is a blood disorder caused insufficient quantities of copper. The body has sufficient iron levels but is unable to utilise it properly in red blood cells due to the lack of copper. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Corpus callosum agenesis -- blepharophimosis -- Robin sequence: A very rare syndrome characterized by abnormal brain development, various facial anomalies, heart defects and other symptoms.
  • Corpus callosum, agenesis of, blepharophimosis Robin type: A very rare syndrome characterized by abnormal brain development, various facial anomalies, heart defects and other symptoms.
  • Cortical hyperostosis-syndactyly: A rare genetic disorder characterized by webbed fingers and thickening and overgrowth of bones.
  • Costello syndrome: A rare genetic disorder characterized by papillomas which may become malignant.
  • Cote-Katsantoni syndrome: A rare condition characterized by osteosclerosis, atrial septal defect, malabsorption, neutropenia, ectodermal dysplasia, growth retardation and mental retardation.
  • Cyanosed nails: Cyanosed nails are fingernails and/or toenails that have a bluish discoloration due to a lack of oxygen in the tissues.
  • Cyanosis: Blueness or purple coloring of skin.
  • Cycloserine-induced Sideroblastic anemia: Cycloserine -induced sideroblastic anemia is a blood disorder caused by taking a drug called Cycloserine. The body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Darier disease: A slowly progressing inherited skin disorder characterized by small brownish warty bumps and nail abnormalities. The skin disorder because the skin cells are not held together properly.
  • Dark nails in children: Dark nails in children refers to a child that has nails that are darker than usual.
  • Deafness -- onychodystrophy -- osteodystrophy -- mental retardation: A very rare inherited disorder involving deafness (D), onychodystrophy (O - nail malformation), osteodystrophy (O - bone malformation) and mental retardation (R).
  • Deafness onychodystrophy dominant form: A rare dominantly inherited disorder characterized by deafness from birth, deformed nails and
  • Deafness, congenital onychodystrophy, recessive form: A very rare inherited disorder involving deafness (D), onychodystrophy (O - nail malformation), osteodystrophy (O - bone malformation) and mental retardation (R).
  • Decreased mean cell haemoglobin: A decreased hemoglobin content of the average red blood cell, calculated from the hemoglobin therein and the red cell count in erythrocyte indices
  • Decreased mean cell haemoglobin concentration: A decreased average haemoglobin concentration in the a specified volume
  • Decreased mean cell volume: A decreased mean red cell volume
  • Del(1) (23-q25): A very rare chromosomal disorder where a portion of the long arm (23q-q25) of chromosome one is missing.
  • Deletion 10pter: A very rare syndrome caused by a chromosomal defect (10p terminal deletion) and can result in a variety of malformations that are similar to DiGeorge syndrome and velocardiofacial syndrome.
  • Deletion 8p: A rare chromosomal disorder involving deletion of genetic material from the short arm (p) of chromosome 8 resulting in various abnormalities. The type and severity of symptoms varies depending on the amount and exact location of the genetic material that is deleted.
  • Dermatitis: Inflammation of the skin.
  • Dermatomyositis: A muscle disease characterized by chronic muscle inflammation resulting in progressive muscle weakness and a characteristic rash.
  • Dermatoosteolysis, Kirghizian type: A rare condition characterized by a variety of abnormalities including missing teeth, recurring skin ulceration, eye problems and nail symptoms.
  • Dermo-odontodysplasia: A very rare syndrome characterized mainly by tooth, skin, hair and nail abnormalities.
  • Diabetes-like symptoms: Symptoms similar to those of diabetes
  • Digitorenocerebral syndrome: A very rare syndrome characterized by numerous abnormalities involving the brain, kidneys, fingers, toes, nails and face as well as mental retardation and vision impairment.
  • Dilantin -- Teratogenic Agent: There is strong evidence to indicate that the use of Dilantin (anti-seizure medication) during pregnancy may cause a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Dilated capillaries of the nail fold: form of capillary abnormalities.
  • Dimorphic anemia: Dimorphic refers to anemia that has two different causes acting together e.g. iron deficiency as well as a Vitamin B12 deficiency.
  • Distal lateral subungual onychomycosis: A fungal infection of the nail which tends to involve start under the nail where it separates from the nail bed. This is the most common form of onychomycosis and the toenails tend to be affected more than the fingernails.
  • Drug-induced Sideroblastic anemia: Drug-induced sideroblastic anemia is a blood disorder caused by drugs such as cycloserine, isoniazid and ethanol. The body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Dunnigan syndrome: A rare metabolic disorder involving abnormal fat distribution where fat accumulates on areas such as the face, shoulders, neck and genitals but gradually disappears from the limbs, trunk and buttocks.
  • Dunningan syndrome: A rare metabolic disorder involving abnormal fat distribution where fat accumulates on areas such as the face, shoulders, neck and genitals but gradually disappears from the limbs, trunk and buttocks.
  • Duplication 5q: A rare chromosomal disorder involving duplication of the long arm (q) of chromosome 5 which results in various abnormalities depending on the size and location of the portion of duplicated genetic material.
  • Dyserythropoietic anemia, congenital type 1: A very rare genetic blood disorder where abnormal red blood cells are made resulting in anemia. Finger and toe abnormalities are also usually present.
  • Dyshidrotic dermatitis: A skin disorder (eczema) that affects the soles of the feet, the palms of the hands and the sides of the fingers. There is no known cause but contributing factors include stress, hot or cold weather, pre-existing atopic condition, metal implants, smoking, and aspirin and oral contraceptive use.
  • Dyskeratosis Congenita: A rare genetic disorder characterized by sking pigmentation abnormalities, nail dystrophy and mucous membrane changes.
  • Dystrophic epidermolysis bullosa: A rare inherited skin blistering condition which can vary in severity depending on how it is inherited. Recessively inherited are more severe than dominantly inherited cases and can cause the loss of patches of skin and scarring which can impair limb function.
  • EEC syndrome: A rare genetic disorder characterized by absence of fingers and toes, ectodermal dysplasia and cleft lip or cleft palate.
  • Ectodermal dysplasia: A group of rare inherited conditions which affect the ectodermal skin layer which includes the skin, hair, teeth and nails.
  • Ectodermal dysplasia anhidrotic: A rare inherited condition involving skin, hair, teeth and nail abnormalities. The condition is characterized by the absence of sweat and sebaceous glands, underdeveloped hair and teeth, characteristic face and other physical deformities.
  • Ectodermal dysplasia mental retardation syndactyly: A rare syndrome characterized by mental retardation, webbed fingers and hair, nail and teeth abnormalities.
  • Ectodermal dysplasia trichoodontoonychial type: A rare syndrome characterized by nail, tooth and hair abnormalities.
  • Ectodermal dysplasia, Margarita type: A rare genetic disorder characterized by mental retardation, webbed digits, cleft lip, cleft palate, sparse hair, reduced sweating and teeth abnormalities. Progressive loss of scalp hair usually results in baldness by adulthood.
  • Ectodermal dysplasia/ skin fragility syndrome: An extremely rare syndrome characterized by fragile skin which blisters and peels, abnormal nails and thickened skin on palms and soles. Skin blistering and peeling starts at birth.
  • Ectrodactyly -- Ectodermal Dysplasia -- Cleft Lip/Palate Syndrome, Type 1: EEC (Ectrodactyly, ectodermal dysplasia, cleft lip/palate) is a rare inherited condition characterized by split hand and foot deformities of variable severity, cleft lip or palate and teeth and hair anomalies. There are two main types of EEC which differ in the origin of the genetic defect. Type 1 is caused by a defect on chromosome 7q11. The severity and type of symptoms and deformities is highly variable.
  • Ectrodactyly -- Ectodermal Dysplasia -- Cleft Lip/Palate Syndrome, Type 3: EEC (Ectrodactyly, ectodermal dysplasia, cleft lip/palate) is a rare inherited condition characterized by split hand and foot deformities of variable severity, cleft lip or palate and teeth and hair anomalies. There are two main types of EEC which differ in the origin of the genetic defect. Type 3 is caused by a defect on chromosome 3q27. The severity and type of symptoms and deformities is highly variable.
  • Ectrodactyly ectrodermal dysplasia: A rare genetic disorder characterized by missing digits and hair, teeth and nail abnormalities. The severity of the hand and foot malformations is variable.
  • Edwards Syndrome: A rare inherited genetic disorder where a portion of chromosome 18 is duplicated. Most affected individuals die during the fetal stage and surviving infants have serious defects and tend to live for only a short while.
  • Ellis -van creveld syndrome:
  • Emanuel syndrome: A rare chromosomal disorder where a portion of chromosome 11 is translocated with a portion of chromosome 22. The disorder involves a wide range of abnormalities such as kidney, genital and heart abnormalities, mental retardation, small head and failure to thrive.
  • Epidermalolysis bullosa: A group of skin disorders characterized by fragile skin which can blister upon little or no trauma to the skin. There are a number of different subtypes with some being inherited and some acquired. The hands and feet are often the main parts of the body affected.
  • Epidermolysis bullosa: A group of rare inherited skin diseases characterized by fragile skin which forms blisters with even minor injuries. The blisters can be painful and can occur anywhere on the skin and even inside the digestive tract.
  • Epidermolysis bullosa dystrophica, Bart type: A rare inherited skin blistering disorder characterized by the development of blisters on the skin and mucous membranes as well as areas of missing skin at birth. Nail abnormalities are also present.
  • Epidermolysis bullosa dystrophica, dominant type: A relatively mild form of the skin disease characterized by fragile, blistered skin.
  • Epidermolysis bullosa simplex with mottled pigmentation: A variant of a skin blistering disease which also involved a skin pigmentation anomaly.
  • Epidermolysis bullosa simplex, Ogna type: An inherited skin blistering condition characterized by blisters on palms and soles.
  • Epidermolysis bullosa, dermolytic: A rare genetic syndrome characterized by fragile skin which blisters easily due to defective skin collagen. The mucosal lining of the mouth and even intestines may be effected in severe cases.
  • Epidermolysis bullosa, junctional: A rare inherited skin disease which is characterized by fragile skin which readily forms skin blisters and can result in fatal complications.
  • Epidermolysis bullosa, pretibial: A rare genetic syndrome characterized by fragile skin which blisters easily due to defective skin collagen. The skin on the front of the shins is usually the main area affected in this form.
  • Epidermolysis bullosa, simplex: A group of skin disorders characterized by fragile skin which can blister upon little or no trauma to the skin. There are a number of different subtypes with some being inherited and some acquired. The hands and feet are often the main parts of the body affected.
  • Epidermolytic epidermolysis bullosa: A group of skin disorders characterized by fragile skin which can blister upon little or no trauma to the skin. There are a number of different subtypes with some being inherited and some acquired. The hands and feet are often the main parts of the body affected.
  • Erythroderma: Condition with thickening and flaking skin
  • Ethanol-induced Sideroblastic anemia: Ethanol-induced sideroblastic anemia is a blood disorder caused by consuming ethanol. The body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Exfoliative dermatitis: Form of dermatitis where skin flakes or falls off.
  • FLOTCH syndrome: A very rare syndrome characterized mainly by kidney stones, completely white nails and cysts that form in oil producing areas of skin.
  • Faciothoracogenital syndrome: A rare syndrome characterized by facial, chest and genital abnormalities.
  • Fairbank disease: A rare inherited disorder that affects the secondary growth centers of bones usually in the hips, knees and ankles and results in mild dwarfism.
  • Fernhoff-Blackston-Oakley syndrome: A very rare syndrome characterized mainly by retarded fetal growth and jaw anomaly as well as various other abnormalities.
  • Fibular hypoplasia or aplasia -- femoral bowing -- oligodactyly: A rare syndrome characterized mainly by abnormalities involving the thighbone, fingers and fibula (calf bone).
  • Finger symptoms: Symptoms affecting any fingers
  • Fingernail bleeding: Usually due to trauma.
  • Fingernail bleeding in children: Fingernail bleeding in children is bleeding under or around a child's fingernail.
  • Fingernail blister: Water filled lesions around the fingernails.
  • Fingernail blueness: A blue discolouration of the fingernail
  • Fingernail bruise: A haematoma that occurs on the fingernail
  • Fingernail bruise in children: Fingernail bruise in children is a purplish or black discoloration of the nail with pain that is the result of the breaking of small blood vessels under the fingernail.
  • Fingernail burning sensation: Abnormal burning sensations felt in the fingernails.
  • Fingernail cold: Abnormal sensation of coldness felt due to inflammation of the connective tissue of the body.
  • Fingernail deformity: Distortion of the fingernail.
  • Fingernail infection: Infection of the fingernails.
  • Fingernail inflammation: Inflammation of the fingernails.
  • Fingernail itch: Finger itch is an unpleasant sensation that evokes the desire or reflex to scratch.
  • Fingernail lump: Irregular swelling on the fingernail.
  • Fingernail rash: Finger rash is change of the skin which affects its color, appearance or texture.
  • Fingernail redness: Redness of the fingernails.
  • Fingernail sensitive: Increased sensitivity of the fingernails to any stimulus.
  • Fingernail spasm: Sudden involuntary contraction of the muscles of the fingers.
  • Fingernail stiff: Lacking ease or comfort of movement of the fingernails.
  • Fingernail symptoms: Symptoms affecting the fingernails
  • Fingernail ulcer: Break in the continuity of the lining skin.
  • Fingernail weakness: Weakness of the finger muscles.
  • Fingers blister: A small pocket of fluid within the upper layers of the skin of the fingers.
  • Fingers bruise: Injury or trauma to the fingers which is often characterized by ruptured blood vessels and discolorations.
  • Finlay-Markes syndrome: A very rare syndrome characterized mainly by scalp, nipple and ear abnormalities.
  • Fitzsimmons-McLachlan-Gilbert syndrome: A very rare syndrome characterized mainly by mental retardation paraplegia and thickened coarse skin on palms and soles.
  • Focal dermal hypoplasia: A rare genetic disorder characterized by bone, skin, teeth and pigmentation abnormalities as well as asymmetry of the face, trunk and extremities.
  • Folate-deficiency anemia: Folate-deficiency anemia is a blood condition characterized by low levels of folate in the body which leads to a reduction in the number of red blood cells. It is usually the result of a poor diet, malabsorption issues or the use of certain medications.
  • Foot symptoms: Symptoms affecting one or both feet
  • Freire-Maia odontotrichomelic syndrome: A rare syndrome characterized by tooth, hair and limb abnormalities.
  • Freire-Maia syndrome: An extremely rare syndrome characterized by tooth, hair and limb abnormalities. The abnormalities can be quite severe in some cases. The parents may have been related in the reported cases.
  • Friedel Heid Grosshans syndrome: A very rare syndrome characterized mainly by kidney stones, completely white nails and cysts that form in oil producing areas of skin.
  • Fryns Syndrome: A rare genetic disorder characterized by diaphragmatic abnormalities, coarse face and abnormal growth or development of ends of fingers and toes.
  • Fuhrmann syndrome: A rare syndrome characterized mainly by abnormalities involving the thighbone, fingers and fibula (calf bone).
  • Fuhrmann-Rieger-de Sousa syndrome: A rare syndrome characterized mainly by abnormalities involving the thighbone, fingers and fibula (calf bone).
  • Fukuda-Miyanomae-Nakata syndrome: A rare syndrome characterized mainly tooth, bone and nail abnormalities as well as anal and urethral anomalies.
  • Fungal infections: Symptoms from various fungal infections
  • Fungal nail infections: Fungal conditions of the toenail or fingernail
  • Generalized pustular psoriasis: This is a rare form of psoriasis is also known as von Zumbusch psoriasis. It can be life-threatening especially in the elderly. It is characterized by the development of pustules in the flexural areas - the backs of the knees, the insides of the elbows, the armpits and the groin. These pustules continue to spread and soon they join to form lakes of pus. The pustules rupture easily and can become infected. This condition can be fatal if the patient gets dehydrated, or the infection spreads to the bloodstream. Generalized pustular psoriasis is often triggered by stopping topical or oral steroids.
  • Goldblatt-Wallis syndrome: A very rare syndrome characterized by mental retardation and an abnormally placed urethral opening in males.
  • Gorlin-Bushkell-Jensen syndrome: A rare disorder characterized by the development of numerous sebaceous cysts (mainly on the back, chest, arms, thighs and scrotum) as well as kidney stones and white nails.
  • Gradual development of white nails: Gradual development of white nails is a slow development of unusual whitening of the nails.
  • Gradual onset of brown nails: Gradual onset of brown nails is the slow development of nails that are discolored brown.
  • Gradual onset of koilonychia: Gradual onset of koilonychia refers to a slow development of a nail disease that causes the nails to become abnormally spoon-shaped.
  • Gradual onset of longitudinal nail grooves: Gradual onset of longitudinal nail grooves is the slow development of ridges in the nails that run in a longitudinal manner.
  • Gradual onset of nail pitting: Gradual onset of nail pitting is a condition in which there is a slow development of pits or depressions in a nail.
  • Gradual onset of yellow nails: Gradual onset of yellow nails is a condition in which there is a slow development of yellowish discoloration on nails.
  • Graeck-Imerslund disease:
  • Grasbeck-Imerslund Disease: A rare inherited disorder characterized by vitamin B12 deficiency which results from the body's inability to absorb vitamin B12 from the foods eaten.
  • Haim-Munk syndrome: A rare inherited disorder involving red, thickened patches of skin on the palms and soles, skin infections and nail and teeth abnormalities.
  • Halal Setton Wang syndrome: A very rare syndrome characterized mainly by eye, teeth, nail and skin abnormalities.
  • Hand symptoms: Symptoms affecting the hand
  • Hay-Wells Syndrome: A rare genetic disorder characterized by ankyloblepharon, ectodermal dysplasia, and cleft lip and/or cleft palate.
  • Hay-Wells syndrome, recessive type: A rare recessively inherited genetic disorder characterized by ankyloblepharon, ectodermal dysplasia, and cleft lip and/or cleft palate. The recessive form of this condition is distinguished by the presence at birth of adhesions between the upper and lower jaws.
  • Heart conditions: Any condition that affects the heart
  • Heart failure: A condition which is characterized by an inability of the heart to pump blood efficiently and effectively
  • Heart symptoms: Symptoms affecting the heart
  • Hematoma: Local collection of clotted blood
  • Hemolytic anemia: A condition which is characterized by anaemia due to the destruction of red blood cells
  • Hepatic failure: loss of normal liver function and metabolism of products by the liver
  • Hereditary hypothyroidism: Hereditary hypothyroidism is a condition in which there is a defect in the thyroid gland which leads to increased production of TSH reduced production of thyroid hormone.
  • Hereditary koilonychia: An inherited anomaly where the nails are flattened or concave-shaped rather than the normal curved shape.
  • Hidrotic ectodermal dysplasia, type Christianson-Fourie: A very rare syndrome characterized mainly by hair and nail abnormalities.
  • High blood pressure: Excessive blood pressure.
  • Horizontal nail ridges: Horizontal nail ridges are nail creases or grooves that develop in a horizontal manner.
  • Horizontal nail ridges in children: Horizontal nail ridges in children refers to furrows in the nails that run in a horizontal manner.
  • Hutchinson Gilford Syndrome: A rare genetic disorder characterized by alopecia and senile-like appearance.
  • Hyperchromic Anemia: Hyperchromic anemia is a blood disorder characterized by red blood cells which contain abnormally high amounts of haemoglobin as well as a reduced number of red blood cells. This anomaly is often caused by such things as Vitamin B12 deficiency and pernicious anemia.
  • Hyperkeratosis of the nails: Hyperkeratosis of the nails is an abnormal thickening of the skin of the nail bed under the fingernails or toenails.
  • Hyperpigmentation of nails: Increased pigmentation of the nail.
  • Hyperthyroidism: The excessive activity of the thyroid gland
  • Hypoalbuminemia: Low levels of albumin (protein) in the blood.
  • Hypocalcaemia: Decreased concentration of calcium in the blood.
  • Hypodontia -- nail dysgenesis: A syndrome that is characterized by the occurrence of nail dysplasia and tooth abnormalities. Primary teeth are usually normal but some secondary teeth may be missing. The toenails tend to be more affected than the fingernails.
  • Hypodontia dysplasia of nails: A syndrome that is characterised by the occurrence of nail dysplasia and tooth abnormalities. Primary teeth are usually normal but some secondary teeth may be missing. The toenails tend to be more affected than the fingernails.
  • Hypomelanosis of Ito: A rare genetic neurocutaneous disorder characterized by unusual patterns of depigmented skin and associated disorders such as seizures, psychomotor retardation and eye abnormalities.
  • Hypothyroid goitre: Goitre is the enlargement of the thyroid gland and hypothyroid state is characterized by increased TSH levels and decreased T3 and T4 levels circulating in the body.
  • Hypothyroidism: The decreased activity of the thyroid gland
  • Ichthyosiform erythroderma, nonbullous congenital: A rare inherited skin disorder characterized by redness, scaling and ultimately thickening of the skin that occurs from birth. The severity of the condition is variable.
  • Ichthyosis -- alopecia -- eclabion -- ectropion -- mental retardation: A very rare syndrome characterized mainly by scaly skin, hair loss, mental retardation and outwardly turned eyelids and lips.
  • Ichthyosis and male hypogonadism: A very rare syndrome characterized mainly by scaly skin and insufficient hormone production by the male gonads.
  • Ichthyosis male hypogonadism: A very rare syndrome characterized mainly by scaly skin and insufficient hormone production by the male gonads.
  • Incontinentia Pigmenti: A rare genetic skin pigmentation disorder characterized by eye, teeth, bone, nail and hair malformations as well as central nervous abnormalities and mental deficiency.
  • Ingrown nails: Inward growth of finger-nails or toe-nails.
  • Inherited spherocytic anemia: Inherited Spherocytic anemia is an inherited blood disorder characterized by red blood cells that are shaped like a sphere (spherocytes) rather than the normal doughnut shape. These abnormal cells are broken down prematurely resulting in a shortage of red blood cells (anemia).
  • Injury: Any damage inflicted in the body
  • Iron deficiency: When there is a deficiency of iron in the body
  • Iron deficiency anemia: Iron-deficiency anemia is a blood condition characterized by low levels of iron in the body which leads to a reduction in the number of red blood cells.
  • Isoniazid-induced Sideroblastic anemia: Drug-induced sideroblastic anemia is a blood disorder caused by taking a drug called isoniazid. The body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Jadassohn-Lewandowsky syndrome: A rare, inherited disorder characterized by thickening of nails, white patches on mouth and anus(leukoplakia) and thickened hard skin on soles and palms.
  • Jeune syndrome: A rare genetic disorder characterized by short limbs, underdeveloped iliac wings and a narrow rigid thoracic cage that often results in asphyxiation.
  • Judge-Misch-Wright syndrome: A very rare syndrome characterized mainly by thickened skin on palms and soles as well as around the mouth.
  • Jugular lymphatic obstruction sequence: A rare disorder caused by obstruction of the jugular lymphatic system due to problems during the fetal stage of development.
  • Kaplan-Plauchu-Fitch syndrome: A very rare syndrome characterized mainly by cone-shaped skull, short stature, deafness and various facial and digital abnormalities.
  • Kawasaki disease: A childhood illness that generally affects the skin, mouth and lymph nodes.
  • Keratosis focal -- palmoplantar, gingival: A rare syndrome characterized mainly by thickened skin on the soles and palms in areas that are under the most trauma e.g. weight-bearing part of sole. The gums also have thickened growths.
  • Keratosis palmoplantar periodontopathy: A very rare inherited condition characterized by dry scaly patches on the skin of the palms and soles, gum and teeth problems and frequent skin infections.
  • Keratosis palmoplantaris -- periodontopathia -- onychogryposis: A rare syndrome characterized by gum disease, nail and skin problems and various other anomalies.
  • Keratosis palmoplantaris papulosa: A rare condition involving thickening of the skin on the palms and soles
  • Kidney symptoms: Symptoms affecting one or both kidneys.
  • Knuckle pads, leukonychia and sensorineural deafness: A very rare syndrome characterized mainly by deafness, knuckle pads and white nails.
  • Koilonychia in children:
  • Kumar levick syndrome: A rare syndrome characterized by missing or abnormal nails, missing fingers, permanently bent fingers and a finger-like thumb.
  • Laband Syndrome:
  • Leg symptoms: Symptoms affecting the leg
  • Leprechaunism: A very rare genetic disorder characterized by insulin resistance which leads to growth delay and endocrine system abnormalities.
  • Leuconychia: A white discoloration of the nails.
  • Leukonychia totalis: A rare nail disorder where the whole of the nail is completely white at birth.
  • Leukonychia totalis -- trichilemmal cysts -- cilliary dystrophy: A very rare syndrome characterized mainly by kidney stones, completely white nails and cysts that form in oil producing areas of skin.
  • Lichen planus: Skin rash
  • Limb symptoms: Symptoms affecting the limbs
  • Limb-mammary syndrome: A rare syndrome characterized by abnormalities of the hand and/or foot as well as absent or underdeveloped mammary glands and nipples. The severity of the deformity is variable. Tooth, nail and sweat gland abnormalities may also be present.
  • Liver symptoms: Symptoms affecting the liver
  • Longitudinal nail grooves in children: Longitudinal nail grooves in children refer to furrows or ruts in a child's fingernails that run lengthwise.
  • Low haemoglobin: Decreased concentration of haemoglobin in the blood.
  • Lower leg symptoms: Symptoms affecting the lower legs, calves and shins.
  • Lung cancer: Lung cancer is a disease of uncontrolled cell growth in tissues of the lung. This growth may lead to metastasis, which is the invasion of adjacent tissue and infiltration beyond the lungs. Most lung tumors are malignant.
  • Lung conditions: Various conditions affecting the lungs or related airways.
  • Lung symptoms: Symptoms affecting one or both lungs.
  • Lymphedema -- ptosis: A very rare syndrome characterized mainly by lymphedema (lymphatic obstruction) in the legs and droopy eyelids.
  • Macrocytic Hyperchromic Anemia: Macrocytic Hyperchromic anemia is a blood disorder characterized by abnormally large red blood cells which contain abnormally high amounts of haemoglobin. There is also a reduced number of red blood cells. This anomaly can be associated with such things as celiac disease or alcoholism.
  • Macrocytic anemia: Macrocytic anemia is a blood disorder where the red blood cells are larger than normal but have low levels of haemoglobin which is needed to carry oxygen throughout the body. The condition usually results from a deficiency of vitamin B12 or folate, digestive problems, malabsorption and certain medications which affect folic acid levels. Various rare inherited disorders may also result in macrocytic anemia e.g. Lesch-Nyhan syndrome. Severity and range of symptom may vary depending on the underlying condition.
  • Malnutrition: Any disorder that relates to inadequate intake of nutrients.
  • Manouvrier syndrome: A very rare syndrome characterized mainly by the failure of the lungs to develop fully, heart defects and thumb abnormalities.
  • Marinesco-Sjogren I: A rare condition characterized by cerebellar ataxia, speaking difficulty, mental retardation, short stature and tooth, hair and nail abnormalities.
  • McGrath Syndrome:
  • Megaloblastic Anemia 1: A rare genetic blood disorder where a defect in the vitamin B12 receptor means that it can't be absorbed from food during digestion. As a result of the low vitamin B12 levels, the body produces increased numbers of abnormal enlarged red blood cells (megaloblasts).
  • Megaloblastic anemia: Megaloblastic anemia, also called pernicious anemia, is a condition in which there is a low number of red blood cells most often caused by a lack of vitamin B12.
  • Megalocytic-Normochromic anemia: Megalocytic-Normochromic is a blood disorder characterized by normal amounts of haemoglobin within abnormally large red blood cells. However, the number of red blood cells is low.
  • Melanoma: Melanoma is the most dangerous type of skin cancer. It is the leading cause of death from skin disease. It involves cells called melanocytes, which produce a skin pigment called melanin. Melanin is responsible for skin and hair color.
  • Meleda Disease: A very rare inherited skin disorder primarily involving dry thick skin patches that develop on the palms of hands and soles of feet. The type and severity of symptoms is variable.
  • Mental mixed retardation -- deafness -- clubbed digits: A rare disorder characterized mainly by mental retardation, deafness and clubbed fingers.
  • Mental mixed retardation deafnes clubbed digits: A rare disorder characterized mainly by mental retardation, deafness and clubbed fingers.
  • Mental retardation, Buenos Aires type: A very rare syndrome characterized mainly by mental retardation, physical retardation, unusual facial appearance and heart and kidney defects.
  • Methahemoglobinemia: Excess methahemoglobin in the blood
  • Micrencephaly corpus callosum agenesis: A very rare disorder characterized by abnormal brain development which results in a very small brain. Patients may die during infancy and survivors suffer mental retardation and other physical abnormalities.
  • Microcytic Anemia: Microcytic anemia is a blood disorder characterized by small red blood cells (erythrocytes). The red blood cells are small due to a failure of haemoglobin synthesis or insufficient quantities of haemoglobin available. The blood disorder is usually caused by conditions such as iron deficiency, chronic diseases and thalassemias.
  • Microcytic Hyperchromic Anemia: Microcytic Hyperchromic anemia is a blood disorder characterized by abnormally small red blood cells which contain abnormally high amounts of haemoglobin. There is also a reduced number of red blood cells. This anomaly can be associated with such things as chronic infections and severe malnutrition.
  • Microcytic hypochromic anemia: Microcytic anemia is a blood disorder characterized by small red blood cells (erythrocytes) which have insufficient haemoglobin and hence have a reduced ability to carry oxygen through the body. The red blood cells are small due to a failure of haemoglobin synthesis or insufficient quantities of haemoglobin available. The blood disorder is usually caused by conditions such as iron deficiency, chronic diseases and thalassemias. The severity and range of symptoms is variable.
  • Microcytic-Normochromic anemia: Microcytic-Normochromic anemia is a blood disorder characterized by normal amounts of haemoglobin within small red blood cells. However the number of red blood cells is low.
  • Mineral deficiency: A deficiency of any minerals in the body
  • Mitral atresia: A rare defect where the mitral valve is closed off. The mitral valve connects the two chambers on the left side of the heart (atrium and ventricle). The blood is therefore unable to flow between the two heart chambers.
  • Moloney syndrome: A very rare syndrome characterized mainly by wasting of the choroids in the eye and sparse, fine hair. The choroid is a layer of blood vessels that lies between the retina and the sclera and delivers blood to the back of the eye.
  • Nail Ridges: Linear elevations that may be either horizontal or vertical on the fingernails or toenails.
  • Nail abnormalities: abnormalities of the nail may be missed if the clinician is not aware of the classic patterns that are seen so infrequently
  • Nail abnormalities in children: Nail abnormalities in children are any type of deformity or irregularity in a child's nails.
  • Nail abnormality: An abnormality of the finger and/or toe nails.
  • Nail bleeding: Bleeding from the nails - usually due to trauma.
  • Nail blister: Water filled lesions around or under the nails.
  • Nail burning sensation: Abnormal burning sensations felt in the nails of the fingers or toes.
  • Nail cold: Abnormal sensation of coldness felt around the nail area.
  • Nail conditions: Any condition that affects the nail
  • Nail deformity: Distortion of the nails of the fingers or toes.
  • Nail discoloration in children: Nail discoloration in children refers to an abnormal coloring of a child's fingernails and/or toenails.
  • Nail discolouration in children:
  • Nail dysplasia, isolated congenital: A rare genetic disorder characterized by abnormal nail development which is usually evident at birth or soon after.
  • Nail infection: Infection of the nails of the fingers or toes.
  • Nail inflammation: Inflammation of the nails of the fingers or toes.
  • Nail itch: Finger itch is an unpleasant sensation that evokes the desire or reflex to scratch.
  • Nail lump: Irregular swelling of the nails of the fingers or toes.
  • Nail pitting in children: Nail pitting in children is abnormal cavities or depressions in a child's nail.
  • Nail rash: Finger rash is change of the skin which affects its color, appearance or texture.
  • Nail redness: Redness of the nails of the fingers or toes.
  • Nail sensitive: Increased sensitivity of the nails to any stimulus.
  • Nail shedding in children: Nail shedding in children is the detachment and loss of a child's nail.
  • Nail spasm: Sudden involuntary contraction of the digit muscles.
  • Nail stiff: Lacking ease or comfort of movement of the nails.
  • Nail ulcer: Break in the continuity of the lining skin around or under the nails.
  • Nail weakness: Weakness of the nails.
  • Nail-Patella Syndrome: A rare inherited disorder characterized by small or absent kneecap and ridged and/or absent nails as well as other abnormalities
  • Navajo poikiloderma: A rare genetic blood disorder found in Navajo populations and characterized by a progressive skin disorder and neutropenia (lack of neutrophils which are needed to fight bacterial infections).
  • Non-hereditary spherocytic anemia: Non-inherited spherocytic anemia is an acquired blood disorder characterized by red blood cells that are shaped like a sphere (spherocytes) rather than the normal doughnut shape. These abnormal cells are broken down prematurely resulting in a shortage of red blood cells (anemia). The blood condition may result from such things as acute, widespread burns to the body, low blood phosphate levels, Zieve's syndrome and toxins from poisonous snakes, spiders and insects.
  • Normocytic anemia: Normocytic anemia is a blood disorder characterized by red blood cells which are of a normal size but present in insufficient quantities. It is often associated with chronic diseases, blood loss, bone marrow problems and kidney disease. It can also be the result of an inherited condition.
  • Normocytic-Normochromic anemia: Megalocytic-Normochromic is a blood disorder characterized by normal amounts of haemoglobin within normal-sized red blood cells. However, the number of red blood cells is low. Conditions such as haemolytic anemia, liver disease and aplastic anemia may be associated with this blood disorder.
  • Nutritional Sideroblastic anemia: Nutritional sideroblastic anemia is a blood disorder caused insufficient quantities of pyridoxine or copper. The body has sufficient iron levels but is unable to utilise it properly in red blood cells due to the lack of pyridoxine or copper. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Nutritional anemia: Nutritional anemia refers to a reduced red blood cell count due to a poor diet which is deficient in iron, folat and/or Vitamin B12.
  • OLEDAID: A rare syndrome characterized mainly by a weak immuned system, bone problems, lymphoedema and hair, teeth and nail abnormalities. Death usually occurs during the first few years of life due to overwhelming infections.
  • Oculo tricho dysplasia: A very rare syndrome characterized mainly by eye, tooth and hair abnormalities
  • Odonto-tricho-ungual-digito-palmarn syndrome: A rare syndrome characterized mainly by the presence of teeth at birth, hair loss and hand and foot malformations.
  • Odontomicronychial dysplasia: A very rare syndrome characterized mainly by tooth and nail abnormalities.
  • Odontoonychodermal dysplasia: A very rare syndrome characterized mainly by tooth, nail and skin abnormalities.
  • Oil spots on nails: Oil spots on nails is a condition in which there are oil spots on the fingernails or toenails.
  • Oil spots on nails in children: Oil spots on nails in children refers to a child who has are oil spots on the fingernails or toenails.
  • Oligodontia, keratitis, skin ulceration and arthroosteolysis: A rare condition characterized by a variety of abnormalities including missing teeth, recurring skin ulceration, eye problems and nail symptoms.
  • Onchyomycosis: A fungal infection of the nail. The toenails tend to be affected more than the fingernails.
  • Onycho-tricho-dysplasia -- neutropenia: A very rare syndrome characterized mainly by hair and nail abnormalities, neutropenia and psychomotor retardation.
  • Onychodystrophy -- deafness: A very rare inherited disorder involving deafness (D), onychodystrophy (O - nail malformation), osteodystrophy (O - bone malformation) and mental retardation (R).
  • Onychodystrophy and anonychia with type B brachydactyly and ectrodactyly: A rare, dominantly inherited disorder characterized abnormal or absent nails, missing fingers, permanently flexed fingers and a broad, finger-like thumb.
  • Onychogryphosis: Thickening, curving and overgrowth of a nail - usually the big toenail.
  • Onycholysis in children: Onycholysis in children refers to a child whose fingernail or toenail has detached painlessly froorm the nail bed, often due to an infection, skin disease, nail irritation, or injury.
  • Onychomadesis in children: Onychomadesis in children refers to occasional shedding of a child's finger nails or toe nails.
  • Onychophagia: Excessive biting or chewing of the fingernails. Also called nail biting.
  • Onychotrichodysplasia and neutropenia: A very rare syndrome characterized mainly by nail, hair and blood abnormalities.
  • Onychotrichodysplasia, chronic neutropenia and mental retardation syndrome: A very rare syndrome characterized mainly by hair and nail abnormalities, neutropenia and mental retardation.
  • Oro acral syndrome: A very rare syndrome characterized mainly by mouth and limb abnormalities.
  • POEMS: A very rare disorder that has widespread effects on the body: P -- polyneuropathy, O -- organopathy, E -- endocrinopathy, M -- monoclonal gammopathy and S -- skin changes.
  • POEMS syndrome: A very rare disorder that has widespread effects on the body: P - polyneuropathy, O - organopathy, E - endocrinopathy, M - monoclonal gammopathy, S - skin changes.
  • Pachyonychia congenita recessive: A rare, recessively inherited disorder where the nails is white and the skin is blistered.
  • Pachyonychia congenital syndrome: A rare genetic ectodermal disorder characterized by thick nails, thick skin on palms and soles and white patches on tongue and inside of cheek.
  • Pachyonychia congenital syndrome type I: A rare genetic ectodermal disorder characterized by thick nails, thick skin on palms and soles and white patches on tongue and inside of cheek.
  • Pachyonychia congenital syndrome type II: A rare genetic ectodermal disorder characterized by thick nails.
  • Pale nails in children: Pale nails in children is a condition in which a child has unusually light colored nails.
  • Pallister-Hall Syndrome: A rare genetic disorder characterized by hypothalamic hamartoblastoma, hypopituitarism, imperforate anus and polydactyly.
  • Palmoplantar keratoderma punctate, hereditary: An inherited disorder characterized by numerous tiny bumps of thickened skin on the palms and soles. The skin develops numerous hyperkeratototic papules which are usually 1-2 mm in size.
  • Paronychia: is often tender bacterial or fungal infection where the nail and skin meet at the side or the base of the finger or toenail
  • Patel-Bixler syndrome: A rare disorder characterized by the association of abnormal thickening of skin on palms and soles, nail abnormalities and alopecia.
  • Pectus excavatum macrocephaly dysplastic nails: A rare syndrome characterized mainly by a sunken chest, large head and abnormal nails.
  • Pemphigus: A rare group of autoimmune skin disorders where blisters or raw sores develop on the skin and mucous membranes. The bodies immune system destroys proteins the hold skin cells together resulting in blistering. The condition can be life-threatening if untreated.
  • Peptic Ulcer: Ulcer on the lining of the stomach or duodenum
  • Peripheral cyanosis in the nail beds: bluish discoloration of the skin and mucous membrane and cyanosis seen in the extremities under the nailbed
  • Peripheral vascular disease: Disease of arteries supplying the legs or sometimes arms
  • Periungual erythema: Periungual erythema is a condition in which redness develops in the area around a fingernail or toenail.
  • Periungual erythema with edema: thickened periungual areas with redness
  • Pernicious anemia: A megaloblastic anaemia due to malabsorption of the vitamin B12
  • Phenytoin -- Teratogenic Agent: There is evidence to indicate that exposure to Phenytoin during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Pili torti -- onychodysplasia: A very rare syndrome characterized mainly by abnormal nails and fragile twisted hair shafts. The condition has been reported in only one family.
  • Pink and white nails in children: Pink and white nails in children refers to a child's nails that have a pink and white coloring.
  • Pitted nails in children: Pitted nails in children refers to a child's nails that are unusually rutted.
  • Pituitary conditions: Any condition that affects the pituitary
  • Plummer's nails: also known as oncholysis
  • Plummer-Vinson syndrome: A disorder characterized by swallowing difficulty associated with severe iron-deficiency anemia.
  • Poikilocytic anemia: Poikilocytic anemia refers a blood disorder characterized by abnormally shaped red blood cells. The abnormal red blood cells may be destroyed prematurely resulting in anemia. The severity of the anemia and hence the severity of symptoms is variable.
  • Pollitt syndrome: A rare condition characterized by brittle hair, mental and growth retardation as well as various other abnormalities. The hair is brittle because due to the reduced amount of sulfur in it and the formation of weak spots (nodes) along it which results in it breaking off easily.
  • Popliteal pterygium syndrome, lethal type: A rare lethal condition characterized by webbing of skin as well as various other physical and mental abnormalities.
  • Primary hypothyroidism: Primary hypothyroidism is a condition in which a defect in the thyroid gland leads to reduced production of thyroid hormone.
  • Protein deficiency:
  • Proud-Levine-Carpenter syndrome: A very rare syndrome characterized mainly by abnormal brain development, a small head and genital abnormalities.
  • Proximal subungual onychomycosis: A fungal infection of the nail which tends to start at the nail fold and affects new nail growth. The infection starts on the top of the nail and then spreads deeper into the nail. This form of onychomycosis tends to occur primarily in AIDS patients.
  • Psoriasis: Psoriasis is an inflammatory skin condition where the defective immune system causes skin cells to grow rapidly. It affects a significant number of people. Arthritis, which can be severe, is associated with the psoriasis in up to a third of cases. Not all patients who are susceptible to the condition will develop it - roughly 10% of those susceptible will actually develop the condition. There are various environmental factors which can trigger the onset of the disease e.g. strep throat (common trigger), some medication, stress and cold weather. Once the disease develops, it may resolve on its own or with treatment or may become a persistent chronic condition. The severity and duration of symptoms is variable.
  • Psoriatic Arthritis, susceptibility to: An inflammatory condition where the defective immune system causes joint inflammation as well as skin cells to grow rapidly causing psoriasis. Not all patients who are susceptible to the condition will develop it. There are various environmental factors which can trigger the onset of the disease e.g. strep throat (common trigger), some medication, stress and cold weather. Once the disease develops, it may resolve on its own or with treatment or may become a persistent chronic condition. The severity and duration of symptoms is variable.
  • Psoriatic arthritis, juvenile form: A type of arthritis associated with psoriasis in children. Psoriasis and arthritis are both inflammatory conditions with one affecting the skin and the other affecting the joints. The arthritis tends to precede the psoriasis.
  • Pterygium, Popliteal, lethal type: A rare lethal condition characterized by webbing of skin as well as various other physical and mental abnormalities.
  • Pulsations in the capillary nail beds: arterial pulsations usually at the finger tips
  • Pyridoxine deficiency-induced Sideroblastic anemia: Pyridoxine deficiency-induced sideroblastic anemia is a blood disorder caused insufficient quantities of pyridoxine. The body has sufficient iron levels but is unable to utilise it properly in red blood cells due to the lack of pyridoxine. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Rabson-Mendenhall syndrome: A very rare genetic disorder involving severe insulin resistance which is where the body fails to be able to use insulin which is needed to control blood sugar levels.
  • Raynaud's phenomenon: A condition where the body extremities sweat and turn blue and cold. Exposure to cold, emotional stress and smoking may trigger the condition. Also known as acrocyanosis.
  • Red purple nails: Red purple nails is a condition in which the fingernails and/or toenails have a red or purple color.
  • Red purple nails in children: Red purple nails in children refers to a child's nails that have a red purple coloring or tint.
  • Red skin at base of nail in children: Red skin at base of nail in children refers to a child who has skin that is red or inflamed at the base of a nail.
  • Reiterís syndrome: A form of reactive arthritis characterized by arthritis, urethritis, conjunctivitis and skin lesions.
  • Renal failure: A condition characterized by a failure of the kidney to excrete toxic metabolites from the body
  • Respiratory conditions: Any condition that affects the respiratory system
  • Rheumatoid arthritis: An autoimmune inflammatory condition which primarily affects the joints
  • Ridged nails: ridges are elongate crest or a linear series of crests on nails. Ridging in nails may be longitudinal or transverse
  • Robinow syndrome, autosomal recessive: A rare genetic disorder characterized by a flat face, short forearms, vertebral anomalies and hypoplastic genitalia.
  • Robinow syndrome, recessive form: A rare genetic disorder characterized by a flat face, short forearms, vertebral anomalies and underdeveloped genitals.
  • Robinson-Miller-Bensimon syndrome: A very rare syndrome characterized by deafness, malformed nails and other abnormalities.
  • Scalp -- ear -- nipple syndrome: A very rare syndrome characterized mainly by scalp, nipple and ear abnormalities.
  • Schafer syndrome: A disorder characterized mainly by thickened skin on the palms and soles, white patches in mouth, mental and growth retardation and hair, nail and eye abnormalities.
  • Schinzel Giedion Syndrome: A rare genetic disorder characterized by many skeletal and genital anomalies, unusual face, mental retardation and kidney malformations.
  • Sclerosteosis: A rare genetic disorder characterized by syndactyly and thickening and overgrowth of bone.
  • Secondary hypothyroidism: Secondary hypothyroidism is a condition in which the activity of the thyroid gland is decreased, due to failure of the pituitary gland or hypothalamus
  • Selective Vitamin B12 malabsorption with Proteinuria: A rare genetic blood disorder where a defect in the vitamin B12 receptor means that it can't be absorbed from food during digestion. As a result of the low vitamin B12 levels, the body produces increased numbers of abnormal enlarged red blood cells (megaloblasts).
  • Selenium poisoning: Excessive exposure to selenium. Selenium is essential to the diet in small amounts but is toxic in large amounts. Poisoning can occur through inhalation or ingestion.
  • Sener syndrome: A very rare syndrome characterized mainly by an unusual facial appearance and an unusual condition where there a cystic spaces around blood vessels as they enter the brain.
  • Separation of the fingernails from the finger beds: also known as oncholysis
  • Separation of the fingernails from the finger beds similar to that in psoriasis: also known as oncholysis
  • Separation of the nail bed: Separation of the nail bed is a condition in which a fingernail or toenail partially or totally pulls away from the nail bed.
  • Septicemia: A systemic inflammatory response to an infection.
  • Septooptic dysplasia -- digital anomalies: A very rare syndrome characterized mainly by finger and toe abnormalities as well as abnormal development of the optic nerve and pituitary gland. Antenatal exposure to sedatives may be a factor in the cause of the disorder.
  • Sick: Feeling ill or off color
  • Sickle Cell Anemia: Sickle cell anemia is an inherited blood disorder characterized by red blood cells which are crescent-shaped rather than the normal doughnut shape. These abnormally shaped red blood cells are unable to function normally and tend to undergo premature destruction which leads to anemia. If the genetic defect which causes the condition is inherited from both parents the condition can be quite severe whereas if it is inherited from only one parent, often there are no symptoms. The abnormally shaped red blood cells can cause problems when they clump together and block blood vessels.
  • Sideroblastic anemia: Sideroblastic anemia is a blood disorder where the body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly. The condition may be inherited, acquired or secondary.
  • Sideroblastic anemia, hereditary: An inherited form of anemia where an enzyme deficiency prevents red blood cells from using iron properly. The red blood cells become overloaded with iron which impairs the blood's ability to carry oxygen.
  • Sideroblastic anemia, pyridoxine-responsive, autosomal recessive: Pyridoxine-responsive sideroblastic anemia is a rare inherited blood disorder characterized by abnormal deposits of iron in the red blood cells which makes them unable to function properly. The condition is inherited in an autosomal recessive manner and responds to treatment with pyridoxine.
  • Sideropenic anemia: Sideropenic anemia is a blood abnormality characterized by reduced iron levels in the plasma. It is a very common form of anemia.
  • Simpson-Golabi-Behmel syndrome: A rare genetic disorder characterized by accelerated growth and other defects.
  • Soto's Syndrome: A rare hereditary disorder characterized by excessive growth during the first few years of life as well as various other mental and physical anomalies.
  • Southwestern Athabaskan genetic diseases: A group of four genetic diseases that are unique to the Navajo and Apache (Southwestern Athabaskan) populations. The disease are Athabaskan severe combined immunodeficiency, Navajo neurohepatopathy, Navajo poikiloderma and Athabaskan brainstem dysgenesis.
  • Spherocytic anemia: Spherocytic anemia is a blood disorder characterized by red blood cells that are shaped like a sphere (spherocytes) rather than the normal doughnut shape. These abnormal cells are broken down prematurely resulting in a shortage of red blood cells (anemia). The condition may be inherited or acquired.
  • Spoon-shaped nails: is when the nail curves upwards and is known as koilonychia
  • Spoon-shaped nails in pregnancy: Spoon-shaped nails, also known as koilonychia, in pregnancy refers to the upward curve of the nails in a woman who is pregnant.
  • Swelling at base of nail: occurs due inflammation
  • Swollen nail: also known as clubbing
  • Swollen nail of both hands: Swollen nail of both hands enlargement of a nail on both hands.
  • T-cell immunodeficiency, congenital alopecia and nail dystrophy: A rare recessively inherited disorder characterized mainly by alopecia, abnormal nails and immunodeficiency (T-cell).
  • TDO type II: A rare genetic ectodermal disorder characterized by kinky hair, tooth enamel and bone abnormalities and differs from type I mainly by a small head and increased long bone density.
  • Taurodontia -- absent teeth -- sparse hair: A very rare syndrome characterized mainly by missing teeth, large tooth pulp chambers and sparse hair.
  • Teebi-Kaurah syndrome: A very rare syndrome characterized mainly by a small head and absent nails.
  • Tertiary hypothyroidism: Tertiary hypothyroidism results from a malfunction of the hypothalamus, the part of the brain that controls the endocrine system.
  • Tetramelic deficiencies -- Ectodermal dysplasia -- deformed ears -- other abnormalities: An extremely rare syndrome characterized by tooth, hair and limb abnormalities. The abnormalities can be quite severe in some cases. The parents may have been related in the reported cases.
  • Thick brittle nails: Thick brittle nails are nails that are unusually dense and break easily.
  • Thick nails: hardening of the nail plate
  • Thick, pitted nails similar to psoriasis: occurs as a result of imperfect nail plate formation in the matrix area
  • Thickened nail plate: Thickened nail plate is an unusually thick or chunky body of the nail.
  • Thickened nails: A condition which is characterized by thickened nails
  • Thinning of nail plate: Thinning of nail plate is a reduction in the density of the body of the nail.
  • Thumb deformity, alopecia, pigmentation anomaly: A very rare syndrome characterized mainly by a deformed thumb, lack of hair and abnormal pigmentation.
  • Thymic-Renal-Anal-Lung dysplasia: A rare syndrome characterized by abnormalities involving the lungs, anus, kidneys and thymus.
  • Thyrotoxicosis: hypermetabolic clinical syndrome resulting from serum elevations in thyroid hormone levels, specifically free thyroxine (T4), triiodothyronine (T3), or both.
  • Tinea: A condition which is characterized by an infection caused by a fungus
  • Tinea unguium: A condition which is characterized by tinea of the nails
  • Toe nail blister: Raised fluid filled lesion in the toes.
  • Toe nail inflammation: Inflammation of the muscles and tendons of the big toe.
  • Toe nail spasm: Involuntary muscle contractions in the big toe.
  • Toe symptoms: Symptoms affecting the toes
  • Toenail Rash: Rash occurring on the toenail.
  • Toenail bruise: Injury to underlying tissues or bone in which the skin is not broken, often characterized by ruptured blood vessels and discolorations.
  • Toenail infection: Infection of the muscles and tendons of the big toe.
  • Toenail pain: Pain affecting a toenail
  • Toenail sensitive: Raised responsiveness of the foot to stimulus.
  • Toenail stiff: Inability to contract the muscles of the big toe.
  • Toenail swelling: Edema of the foot.
  • Toenail symptoms: Symptoms of the nails on the toes
  • Tooth and nail syndrome: A genetic condition which affects the teeth and nails
  • Toxin-induced Sideroblastic anemia: Toxin-induced sideroblastic anemia is a blood disorder caused by toxins such as lead or zinc poisoning. The body has sufficient iron levels but is unable to utilise it properly in red blood cells. The iron becomes abnormally deposited in red blood cells which make them unable to function properly.
  • Trichinosis: Worm infection usually caught from pigs
  • Tricho odonto onycho dermal syndrome: A very rare syndrome characterized by hair, tooth, nail and skin abnormalities.
  • Tricho-dento-osseous syndrome: A rare genetic disorder characterized by kinky hair, tooth enamel and bone abnormalities. There are two different subtypes with type I being distinguished from type II by the presence of a small head and increased density in the long bones.
  • Tricho-dento-osseous syndrome II:
  • Tricho-dento-osseous syndrome type:
  • Tricho-dento-osseous syndrome type I: A rare genetic ectodermal disorder characterized by kinky hair, tooth enamel and bone abnormalities.
  • Tricho-odonto-onychial dysplasia: A very rare syndrome characterized by abnormal skull calcification, reduced scalp hair and nail and tooth enamel abnormalities.
  • Tricho-onychic dysplasia: A rare genetic syndrome characterized by hair and nail abnormalities.
  • Trichorhinophalangeal Syndrome Type I:
  • Trichorhinophalangeal syndrome type 1: A rare genetic disorder characterized by bulbous nose, sparse hair and coning of epiphyses.
  • Trichorrhexis nodosa syndrome: A rare condition characterized by brittle hair, mental and growth retardation as well as various other abnormalities. The hair is brittle because due to the reduced amount of sulfur in it and the formation of weak spots (nodes) along it which results in it breaking off easily.
  • Trichothiodystrophy, type C: A rare condition characterized by brittle hair, mental and growth retardation as well as various other abnormalities. The hair is brittle because due to the reduced amount of sulfur in it and the formation of weak spots (nodes) along it which results in it breaking off easily.
  • Trichothiodystrophy-neurocutaneous Syndrome: A rare condition characterized by brittle hair, mental and growth retardation as well as various other abnormalities. The hair is brittle because due to the reduced amount of sulfur in it and the formation of weak spots (nodes) along it which results in it breaking off easily.
  • Trichothiodystrophy-neurotrichocutaneous Syndrome of Pollitt: A rare condition characterized by brittle hair, mental and growth retardation as well as various other abnormalities. The hair is brittle because due to the reduced amount of sulfur in it and the formation of weak spots (nodes) along it which results in it breaking off easily.
  • Trigonocephaly -- bifid nose -- acral anomalies: A rare syndrome characterized mainly by a prominent triangular shaped forehead, short head, bulbous nose, small jaw, large mouth, poor muscle tone and foot abnormalities.
  • Trigonocephaly -- broad thumbs: A rare syndrome characterized mainly by broad thumbs and a prominent triangular shaped forehead.
  • Trisomy 19 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 19 in some of the body's cells. Some cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.
  • Trisomy 22 mosaicism: A very rare chromosomal disorder where there is an extra copy of chromosome 22 in some of the body's cells. Some cases with this chromosomal abnormality have no clinical symptoms. The presence of abnormalities in some cases is dependent on which body cells contain the chromosomal defect.
  • Trueb-Burg-Bottani syndrome: A very rare genetic syndrome characterized by hair, teeth and nail abnormalities as well as webbed fingers.
  • Tuffli-Laxova syndrome: A rare disorder characterized tooth, nail and skin abnormalities as well as an adrenal cyst.
  • Turner Syndrome: Rare chromosome syndrome with one X but no second X or Y chromosome.
  • Unusual facies and autosomal dominant hypohidrotic ectodermal dysplasia: A rare syndrome characterized mainly by an unusual facial appearance and hair, nail, teeth and sweating abnormalities.
  • Ventruto Digirolamo Festa syndrome: A rare syndrome characterized primarily by premature fusion of skull bones and finger, toe and hip abnormalities.
  • Vitamin B12 Deficiency: A deficiency of Vitamin B12 primarily causes anemias the body is unable to make sufficient quantities of normal red blood cells. Severe cases can lead to permanent nervous system problems. The vitamin B12 deficiency can result from absorption problems, insufficient dietary intake, certain medications (e.g. metformin), inherited conditions (e.g. transcobalamin deficiency) and certain chronic parasitic intestinal infestations.
  • Vitamin deficiency: When there is any deficiency of vitamins in the body
  • Watermelon stomach: The dilation of the blood vessels in the antral of the stomach
  • Weaver Syndrome: A syndrome that is considered a variant of the Marshall-Smith syndrome
  • White nails: White or pale nails.
  • White nails in children: White nails in children is a condition in which a child has unusually white nails.
  • Williams Syndrome: A syndrome characterised by mental retardation, facial abnormalities and emotional instability
  • Witkop syndrome: A syndrome that is characterised by the occurrence of nail dysplasia and tooth abnormalities due to a mutation in the MSX1 gene
  • X-linked sideroblastic anaemia:
  • X-linked sideroblastic anemia: X-linked sideroblastic anemia is a rare inherited blood disorder characterized by abnormal deposits of iron in the red blood cells which makes them unable to function properly. The body continues to absorb more iron from digesting food in order to try and correct the problem but this simply leads to excessive iron being deposited in body tissues as the it can't use the iron properly. The severity of the condition is variable.
  • Yellow nail syndrome: A rare nail condition characterized by thickened yellow nails as well as swelling of parts of the body due to lymphatic drainage problems resulting from blocked or damaged lymphatic system.
  • Yellow nails in children: Yellow nails in children is a condition in which a child has yellow nails.
  • Yunis Varon syndrome: A multisystem genetic disease that affects the skeletal system in particular
  • Zanier-Roubicek syndrome: An inherited syndrome characterized by reduced sweating, hyperthermia, sparse hair, missing teeth and brittle nails.
  • Zimmerman-Laband syndrome: A rare inherited condition characterized by fibrosis of the gums and ear, nose, nail and finger abnormalities.

Conditions listing medical symptoms: Nail symptoms:

The following list of conditions have 'Nail symptoms' or similar listed as a symptom in our database. This computer-generated list may be inaccurate or incomplete. Always seek prompt professional medical advice about the cause of any symptom.

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Conditions listing medical complications: Nail symptoms:

The following list of medical conditions have 'Nail symptoms' or similar listed as a medical complication in our database.
Last revision: Nov 3, 2003

 

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