Diagnostic Tests for Paleness
Diagnostic Test list for Paleness:
The list of diagnostic tests
mentioned in various sources as
used in the diagnosis of Paleness
- Physical examination
- Look for signs of anemia - e.g. pallor of skin, pallor of nail beds and sclera of eyes.
- Look for signs of heart failure including low blood pressure, increased pulse rate, heart murmur, crackles in lungs and swollen ankles
- Looking for possible causes of anemia - e.g. signs of chronic liver failure, neurological signs suggesting possible pernicious anemia.
- Examine for enlarged thyroid which may indicate presence of thyroid disease associated with vitiligo
- Examine for nystagmus (jerky movements of the eyes), translucency of the iris and reduced visual acuity which are always present in albinism
- Blood tests
- Full blood count - looking at size of red blood cells which helps diagnose type of anemia ( e.g. if small size likely iron deficiency or thallasaemia; if large cell size likely Vitamin B12 deficiency ,folate deficiency, drug toxicity; if normal cell size can be chronic disease , hemolysis, renal failure ). Vitamin B12 due to pernicious anemia is associated with vitiligo.
- Hemoglobin level to establish severity of anemia
- Thyroid function tests, looking for thyroid disease associated with vitiligo
- Fasting blood glucose, looking for diabetes mellitus associated with vitiligo
- ACTH stimulation test looking for Addison's disease associated with vitiligo
- Phenylalanine concentration if suspect phenylketonuria which has reduced pigmentation of the skin
- Iron studies to detect iron deficiency ( i.e. low serum iron and ferritin, high transferring)
- Vitamin B12 and folate levels - to detect deficiency which may cause anemia.
- Haptoglobin - reduced levels in hemolysis , Vitamin B12 and folate deficiency, severe hemorrhage.
- Thallasaemia screen by Hemoglobin electrophoresis - if small red cell size is out of proportion to mild anemia.
- Rheumatoid factor, ANA antibodies, ENA antibodies, dsDNA antibodies, antinuclear and anticentromere antibodies to diagnose possible causes of Raynaud's phenomenon
- Stool examination - for occult blood to detect gastrointestinal bleeding.
- Bone marrow examination- if more information is required to establish diagnosis
- Skin scraping - for microscopy may show hyphae with spores characteristic of the yeast infection that is responsible for pityriasis versicolor.
- Skin biopsy - may be required e.g. microscopically vitiligo has complete absence of melanocytes (pigment producing cells).
Home Diagnostic Testing
These home medical tests may be relevant to Paleness causes:
Conditions listing medical symptoms: Paleness:
The following list of conditions
have 'Paleness' or similar
listed as a symptom in our database.
This computer-generated list may be inaccurate or incomplete.
Always seek prompt professional medical advice about the cause
of any symptom.
Select from the following alphabetical view of conditions which
include a symptom of Paleness or choose View All.
Conditions listing medical complications: Paleness:
The following list of medical conditions have 'Paleness'
or similar listed as a medical complication in our database.
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