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Glossary for Tacrolimus -- Teratogenic Agent

  • Drug-related conditions: Medical conditions related to drug usage, including adverse reactions, intoxication, and overdose.
  • Leukeran -- Teratogenic Agent: There is evidence to indicate that exposure to Leukeran (a chemotherapy drug) during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Meningocele: A condition which is characterized by a protrusion of the meninges of the brain or spinal cord through a defect in the spinal cord
  • Multicystic Renal Dysplasia: A congenital kidney defect where the renal cortex has multiple abnormally cysts which can be of varying sized. One or both kidneys may be affected to varying degrees which results in variable severity of symptoms. Often there are other associated kidney defects which can also affect the prognosis of the condition. If both kidneys are involved, death usually occurs around the time of birth but if only one kidney is involved, there are usually no symptoms.
  • Pregnancy-related conditions: Any condition that is related to or caused by pregnancy
  • Teratogen-related conditions: Medical conditions related to "teratogens", i.e. substances that can cause birth defects by fetal exposure.


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