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Glossary for Vaccine-related conditions

  • Congenital vaccinia: Congenital vaccinia is where the fetus becomes infected with vaccinia. This can occur when vaccination is administered during pregnancy - vaccination during the third trimester appears to be the most likely to result in fetal infection. The newborn is born with severe skin lesions and death generally occurs before or soon after birth.
  • Disseminated Vaccinia: Disseminated vaccinia is a serious complication of smallpox vaccination. The condition involves progressive death of tissue (necrosis) at the site of the vaccination. The condition is relatively rare but can result in death so prompt diagnosis and treatment is essential. People with AIDS, immunodeficiencies, cancer, receiving immunosuppressive therapies or have some other form of immune system defect are particularly susceptible to this complication.
  • Eczema vaccinatum: A rare condition where a person who has eczema and is exposed to vaccinia through vaccination. The condition can occur even if the inoculation doesn't occur directly onto eczematous skin. The virus can also be transferred to an eczema sufferer from a recently vaccinated person. Severe untreated cases can result in death.
  • Generalized vaccinia: Generalized vaccinia is a widespread blistered skin rash that develops in some people following smallpox vaccination. The rash usually covers the trunk of the body but can cover all of the body in some cases.
  • Hepatitis C Vaccine -- Teratogenic Agent: There is evidence to indicate that exposure to Hepatitis C Vaccine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Meningococcal Vaccine -- Teratogenic Agent: There is evidence to indicate that exposure to Meningococcal Vaccine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Ocular vaccinia: Ocular vaccinia is a smallpox infection of the eye. The infection usually occurs through eye contact with a hand contaminated with the virus.
  • Post-vaccinial encephalitis: Post-vaccinial encephalitis is a brain infection that occurs after a smallpox vaccination.
  • Progressive Vaccinia: Progressive vaccinia is a serious complication of smallpox vaccination. The condition involves progressive death of tissue (necrosis) at the site of the vaccination. The condition is relatively rare but can result in death so prompt diagnosis and treatment is essential. People with AIDS, immunodeficiencies, cancer, receiving immunosuppressive therapies or have some other form of immune system defect are particularly susceptible to this complication.
  • Vaccine-preventable diseases: Any disease that can be prevented by the administration of a vaccine
  • Vaccinia: A cowpox virus that was initially used for human smallpox vaccines.
  • Vaccinia gangrenosa: Vaccinia gangrenosa is a serious complication of smallpox vaccination. The condition involves progressive death of tissue (necrosis) at the site of the vaccination. The condition is relatively rare but can result in death so prompt diagnosis and treatment is essential. People with AIDS, immunodeficiencies, cancer, receiving immunosuppressive therapies or have some other form of immune system defect are particularly susceptible to this complication.
  • Vaccinia keratitis: Vaccinia keratitis is an eye condition that occurs when the cornea is exposed to the smallpox virus. This exposure is most likely to occur when a person rubs their eyes after handling or bathing a recently vaccinated child. Symptoms may be severe and permanent damage to vision may result.
  • Vaccinia necrosum: Vaccinia necrosum is a serious complication of smallpox vaccination. The condition involves progressive death of tissue (necrosis) at the site of the vaccination. The condition is relatively rare but can result in death so prompt diagnosis and treatment is essential. People with AIDS, immunodeficiencies, cancer, receiving immunosuppressive therapies or have some other form of immune system defect are particularly susceptible to this complication.
  • Vaccinophobia: An exaggerated or irrational fear of vaccines or vaccination.
  • Varicella Vaccine -- Teratogenic Agent: There is evidence to indicate that exposure to Varicella Vaccine during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.
  • Yellow Fever Vaccine -- Teratogenic Agent: There is evidence to indicate that exposure to Yellow Fever Vaccine during pregnancy or within ten days of conception, may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. The likelihood and severity of defects may be affected by the level of exposure and the stage of pregnancy that the exposure occurred at.

 

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