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Sunburn or general photosensitivity?: Sunburn is normally caused by UV-B radiation which penetrates the epidermis and the superficial dermis which release substances such as leucotrienes and histamines can cause redness and pain. Severe sunburn may develop on relatively dull days because thin clouds filter UV- B poorly. The clinical presentations may be mild eythema with minimal discomfort to severe burns such as vesicles, bullae, hypotension and fever. It must be differentiated from that of genearl sensitivity caused by certain drugs such as thiazides, sulphonamides, NSAID's and grisseofluvin, photocontact dermatitis and acute systemic lupus erythematosus....read more »
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