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Diseases » Werner syndrome » Inheritance

Inheritance and Genetics of Werner syndrome

Genetics of Werner syndrome:

Werner syndrome is an inherited genetic disease.

Werner syndrome: Genetics Information

Genetics of Werner syndrome: The disorder is inherited and transmitted as an autosomal recessive trait. Cells from WS patients have a shorter lifespan in culture than do normal cells. The gene for Werner disease (WRN) was mapped to chromosome 8 and cloned: by comparing its sequence to existing sequences in GenBank, it is a predicted helicase belonging to the RecQ family. However, it has yet to be shown to have real helicase activity (as a DNA unwinder important for DNA replication). The molecular role of WRN in Werner syndrome therefore remains to be proven, as does any role it might have in the aging process in general. (Source: Genes and Disease by the National Center for Biotechnology)

About inheritance and genetics:

Inheritance of Werner syndrome refers to whether the condition is inherited from your parents or "runs" in families. The level of inheritance of a condition depends on how important genetics are to the disease. Strongly genetic diseases are usually inherited, partially genetic diseases are sometimes inherited, and non-genetic diseases are not inherited. For general information, see Introduction to Genetics.


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