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Causes of X-Linked Agammaglobulinemia

Inheritance of X-Linked Agammaglobulinemia

X-linked recessive diseases are usually inherited by males from their mother. Rare cases of sporadic genetic...more »

X-Linked Agammaglobulinemia Causes: Male-Female Gender Ratio

Gender of Patients for X-Linked Agammaglobulinemia: Boys only (X-linked recessive)....more »

Gender Profile of X-Linked Agammaglobulinemia: Only boys get XLA. That is because girls have two sets of X chromosomes, and the normal copy compensates for the... (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID) ...more »

X-Linked Agammaglobulinemia: Related Medical Conditions

To research the causes of X-Linked Agammaglobulinemia, consider researching the causes of these these diseases that may be similar, or associated with X-Linked Agammaglobulinemia:

X-Linked Agammaglobulinemia: Causes and Types

Causes of Broader Categories of X-Linked Agammaglobulinemia: Review the causal information about the various more general categories of medical conditions:

What causes X-Linked Agammaglobulinemia?

Causes: X-Linked Agammaglobulinemia: Genetic defect in the gene producing a protein called btk for B-cell development.
Alternations in a gene found on the X chromosome cause XLA. This gene normally produces a protein called btk, which is required for B-cell development. (Source: excerpt from Primary Immune Deficiency, NIAID Fact Sheet: NIAID)

Related information on causes of X-Linked Agammaglobulinemia:

As with all medical conditions, there may be many causal factors. Further relevant information on causes of X-Linked Agammaglobulinemia may be found in:


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