Assessment
Questionnaire

Have a symptom?
See what questions
a doctor would ask.
 

X-linked Genetic Diseases in Wikipedia

Note:Wikipedia is a user-contributed encyclopedia and may not have been reviewed by professional editors (See full Wikipedia disclaimer)

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "X-linked dominant". (Source - Retrieved 2006-09-07 14:24:28 from https://en.wikipedia.org/wiki/X-linked_dominant)

Introduction

X-linked dominant is mode of inheritance in which a gene on the X chromosome is dominant$[1]$. Females are more frequently affected than males, although any X-linked dominant gene is not sex linked. The chance of passing on an X-linked dominant disorder differs between men and women.

This inheritance pattern is less common than X-linked recessive.

Inheritance

Females usually have two X chromosomes, while most males have one X and one Y chromosome. If a child has inherited the mutation from the X chromosome of one of their parents they will have the condition. A woman with an X-linked dominant disorder has a 50% chance of having an affected daughter or son with each pregnancy. The sons of a man with an X-linked dominant disorder will not be affected, but his daughters will all inherit the condition.

Some X-linked dominant conditions such as Aicardi Syndrome are fatal to boys, therefore only girls with these conditions survive. Similarly, individuals with Klinefelter's Syndrome are referred to as "47,XXY Males".

See also

References

  1. X-linked Dominant: Incontinentia pigmenti - Lucile Packard Children's Hospital
 

By using this site you agree to our Terms of Use. Information provided on this site is for informational purposes only; it is not intended as a substitute for advice from your own medical team. The information on this site is not to be used for diagnosing or treating any health concerns you may have - please contact your physician or health care professional for all your medical needs. Please see our Terms of Use.

Home | Symptoms | Diseases | Diagnosis | Videos | Tools | Forum | About Us | Terms of Use | Privacy Policy | Site Map | Advertise