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Treatments for X-linked sideroblastic anemia

Treatment List for X-linked sideroblastic anemia

The list of treatments mentioned in various sources for X-linked sideroblastic anemia includes the following list. Always seek professional medical advice about any treatment or change in treatment plans.

  • Copper - possibly used for related copper deficiency
  • Vitamin B6 - possibly used for related vitamin B6 deficiency
  • Identify and treat underlying condition. Iron supplementation, vitamin C supplements are also usually advised in order to increase iron absorption
  • Vitamin B6 to prevent iron overload in mild cases. Severe cases may require blood transfusion and desferrioxamine treatment to remove excess iron
  • Treatment of sideroblastic anemia varies depending on the underlying cause. Treatments include:
    • Pyridoxine (Vitamin B6) - effective in many acquired and some congenital forms of the disease
    • Thiamine (Vitamin B1) - may be useful in certain types of sideroblastic anemia
    • Folate - may reverse siderobalstic changes in some patients and should be used in conjunction with pyridoxine
    • Blood transfusion - for significant anemia not responsive to pyridoxine
    • Chelation therapy to prevent and treat iron overload associated with regular transfusions
    • Other treatments - cyclophosphamide, chloroquine, Coenzyme Q10 have been used with some success
    • Bone marrow transplantation has been used in selected patients

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